N-(pyridin-3-yl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrazine-3-carboxamide | 1219694-48-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-(pyridin-3-yl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrazine-3-carboxamide
• 英文别名: N-pyridin-3-yl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-3-carboxamide
• CAS: 1219694-48-0
• 化学式: C₁₂H₁₃N₅O
• 分子量: 243.268
• InChiKey: NWRLBLDLQBAFLV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  71.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N-(pyridin-3-yl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrazine-3-carboxamide 、 硫酸二甲酯 以 乙腈 为溶剂， 反应 14.0h， 以28.4%的产率得到1-(pyridin-3-yl)-5-methyl-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrazine-3-carboxamide
  参考文献：
  名称：

  [EN] PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS
  [FR] COMPOSÉS PYRAZOLIQUES UTILISABLES DANS LA LUTTE CONTRE LES INVERTÉBRÉS NUISIBLES

  摘要：

  公开号：

  WO2010034738A3
• 作为产物：
  描述：

  N-pyridin-3-ylpyrazolo[1,5-a]pyrazine-3-carboxamide 在 sodium tetrahydroborate 作用下， 以 甲醇 、 水 为溶剂， 反应 14.0h， 以56%的产率得到N-(pyridin-3-yl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrazine-3-carboxamide
  参考文献：
  名称：

  [EN] PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS
  [FR] COMPOSÉS PYRAZOLIQUES UTILISABLES DANS LA LUTTE CONTRE LES INVERTÉBRÉS NUISIBLES

  摘要：

  公开号：

  WO2010034738A3

文献信息

• PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS
  申请人：BASF SE

  公开号：EP2346335A2

  公开（公告）日：2011-07-27
• Pyrazole Compounds for Controlling Invertebrate Pests
  申请人：Groß Steffen

  公开号：US20110173726A1

  公开（公告）日：2011-07-14

  The present invention relates to a method for controlling invertebrate pests which method comprises treating the pests, their food supply, their habitat or their breeding ground or a plant, seed, soil, area, material or environment in which the pests are growing or may grow, or the materials, plants, seeds, soils, surfaces or spaces to be protected from pest attack or infestation with a pesticidally effective amount of a pyrazole compound of formulae I or II or a salt or an N-oxide thereof, wherein A is a pyrazole radical of the formulae A1 or A2, wherein # denotes the binding; D is a 5- or 6-membered heterocyclic radical fused to the pyrazole moiety; R p1 , R p2 and R px are H, halogen, CN, NO 2 , C 1 -C 10 -alkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -alkynyl, etc.; n is 0 to 4; or two radicals R px bound to the same ring-member may form an oxo substituent, or two radicals R px bound to adjacent ring-members may form a 3- to 7-membered fused cyclic radical; B is N or CR 4 , wherein R 4 is H, halogen, CN, NO 2 , C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy, etc.; X 1 is S, O or NR 1a , wherein R 1a is H, C 1 -C 10 -alkyl, etc.; X 2 is O 2a , NR 2b R 2c or S(O) m R 2d , wherein m is 0, 1 or 2; R 2a is C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 3 -C 6 -cycloalkyl, etc.; R 2b , R 2c are H, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 3 -C 6 -cycloalkyl, etc.; R 2d is C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 3 -C 6 -cycloalkyl, etc.; R 1 is H, CN, C 1 -C 10 -alkyl, C 1 -C 10 -haloalkyl, C 3 -C 10 -cycloalkyl, etc.; R 2 , R 3 and R 5 are H, halogen, CN, NO 2 , C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy, etc., to a method for protecting plant propagation material and/or the plants which grow threfrom, to plant propagation material comprising at least one compound of formulae I or II, to a method for treating or protecting and animal from infestation or infection by parasites, to novel pyrazole compounds of formulae I or II and agricultural composition containing those compounds.
• US8853125B2
  申请人：——

  公开号：US8853125B2

  公开（公告）日：2014-10-07