N,N-dimethyl-2-(3-(3-methyl-1,4-diphenyl-1H-pyrazol-5-yl)phenyl)ethanamine | 1286246-60-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N,N-dimethyl-2-(3-(3-methyl-1,4-diphenyl-1H-pyrazol-5-yl)phenyl)ethanamine
• 英文别名: N,N-dimethyl-2-[3-(5-methyl-2,4-diphenylpyrazol-3-yl)phenyl]ethanamine
• CAS: 1286246-60-3
• 化学式: C₂₆H₂₇N₃
• 分子量: 381.52
• InChiKey: BXZPAUCNAYMDLM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  21.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Heterocycyl-substituted-alkylamino phenyl derivatives, their preparation and use as medicaments
  申请人：Laboratorios del. Dr. Esteve, S.A.

  公开号：EP2308850A1

  公开（公告）日：2011-04-13

  The present invention relates to heterocyclyl-substituted alkylamino phenyl derivatives of formula (I), to processes for the preparation thereof, to medicaments comprising them as well as to their use for the preparation of a medicament for the treatment of 5HT7 receptor mediated diseases or conditions.

  本发明涉及公式（I）的杂环取代烷基氨基苯基衍生物，以及其制备方法、包含它们的药物以及它们用于制备用于治疗5HT7受体介导的疾病或症状的药物的用途。
• [EN] HETEROCYCYL-SUBSTITUTED-ALKYLAMINO PHENYL DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS<br/>[FR] DÉRIVÉS ALKYLAMINOPHÉNYLES À SUBSTITUTION HÉTÉROCYCLYLE, LEUR PRÉPARATION ET LEUR UTILISATION EN TANT QUE MÉDICAMENTS
  申请人：ESTEVE LABOR DR

  公开号：WO2011042302A1

  公开（公告）日：2011-04-14

  The present invention relates to heterocyclyl-substituted alkylamino phenyl derιvatives (I) to processes for the preparation thereof, to medicaments comprising them as well as to their use for the preparation of a medicament for the treatment of 5HT7 receptor mediated diseases or conditions. In the compounds (I) x-y-z together form -N-N=CR1- or =C-NR2 -N=.

  本发明涉及杂环取代烷基氨基苯基衍生物（I），以及其制备方法，包括将其作为药物的药物以及用于制备治疗5HT7受体介导的疾病或症状的药物的用途。在化合物（I）中，x-y-z共同形成-N-N=CR1-或=C-NR2-N=。
• HETEROCYCYL-SUBSTITUTED-ALKYLAMINOPHENYL DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS
  申请人：Garcia-Lopez Monica

  公开号：US20120322842A1

  公开（公告）日：2012-12-20

  The present invention relates to heterocyclyl-substituted alkylamino phenyl derivatives (I) to processes for the preparation thereof, to medicaments comprising them as well as to their use for the preparation of a medicament for the treatment of 5HT7 receptor mediated diseases or conditions. In the compounds (I) x-y-z together form —N—N═CR 1 — or ═C—NR 2 —N═.

  本发明涉及杂环取代的烷基氨基苯衍生物（I），其制备过程，包含它们的药物以及它们用于制备治疗5HT7受体介导的疾病或病状的药物的用途。在化合物（I）中，x-y-z共同形成—N—N═CR1—或═C—NR2—N═。