5,7-Dibrom-O,N-diacetylindoxyl | 108870-76-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 5,7-Dibrom-O,N-diacetylindoxyl
• 英文别名: 3-acetoxy-1-acetyl-5,7-dibromo-indole；3-Acetoxy-1-acetyl-5,7-dibrom-indol；(1-Acetyl-5,7-dibromoindol-3-yl) acetate
• CAS: 108870-76-4
• 化学式: C₁₂H₉Br₂NO₃
• 分子量: 375.016
• InChiKey: GOODJGABBQDJNK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.75
• 重原子数：
  18.0
• 可旋转键数：
  1.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  48.3
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  5,7-Dibrom-O,N-diacetylindoxyl 在 sodium hydroxide 、 水 作用下， 生成 5,7-Dibromindoxyl-acetat
  参考文献：
  名称：

  Holt; Sadler, Proceedings of the Royal Society of London. Series B, Biological sciences, 1958, vol. 148, p. 481,491,493

  摘要：

  DOI：
• 作为产物：
  描述：

  4,6-Dibrom-phenylglycin-2-carbonsaeure 、 乙酸酐 在 sodium acetate 作用下， 生成 5,7-Dibrom-O,N-diacetylindoxyl
  参考文献：
  名称：

  Holt; Sadler, Proceedings of the Royal Society of London. Series B, Biological sciences, 1958, vol. 148, p. 481,491,492

  摘要：

  DOI：

文献信息

• DETECTING MICROBIAL INFECTION IN WOUNDS
  申请人：SYNOVO GMBH

  公开号：US20210088518A1

  公开（公告）日：2021-03-25

  The disclosed technology relates to chemical entities for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The disclosed technology further relates to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic action on specific moieties and/or reaction sites. The disclosed technology additionally relates to detection of pathogenic, e.g., bacterial and/or viral substances, such as enzymes and substrates, at the wound situs. Additional disclosure relates to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.