4-chloro-8-ethoxy-3-ethyl-3H-triazolo[4,5-g]quinoline | 1089197-53-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并三唑类
• 英文名称: 4-chloro-8-ethoxy-3-ethyl-3H-triazolo[4,5-g]quinoline
• CAS: 1089197-53-4
• 化学式: C₁₃H₁₃ClN₄O
• 分子量: 276.725
• InChiKey: SBGFZCVLYPLDFQ-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  硫酸二乙酯 、 8H-1,2,3-Triazolo[4,5-g]quinolin-8-one, 4-chloro-1,5-dihydro- 在 caesium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 0.25h， 以18%的产率得到4-chloro-8-ethoxy-1-ethyl-1H-triazolo[4,5-g]quinoline
  参考文献：
  名称：

  Reactions of Alkylation of Biologically Interesting Triazolo[4,5-g]quinolines and Triazolo[4,5-g]quinoline-1-oxides with Electrophilic Reagents

  摘要：

  With the aim to improve the biological activities discovered for compounds containing the triazolo[4,5-g]quinoline nucleus, we describe the chemical behaviour of 4-chlorotriazolo[4,5-g]quinolines (1a,b) and some its triazolo-N(1)-oxide derivatives (1c-e and II) with electrophilic reagents in order to optimize the synthetic pathways for obtaining both mixtures of N(1,2,3)-alkyl isomers and selectively N(1)-O-alkyl derivatives.

  DOI：

  10.3987/com-08-11415