| 1234565-52-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 1234565-52-6
• 化学式: C₃₃H₆₆O₁₀S₄
• 分子量: 751.145
• InChiKey: IFVYEECIUYZXNF-ZPZOKNLESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.33
• 重原子数：
  47.0
• 可旋转键数：
  36.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  136.3
• 氢给体数：
  4.0
• 氢受体数：
  14.0

反应信息

• 作为产物：
  描述：

  (2R,3R,4S,5S,6S)-3,4,5-tris(allyloxy)-2-((allyloxy)methyl)-6-(heptyloxy)tetrahydro-2H-pyran 、 2-巯基乙醇 在 偶氮二异丁腈 作用下， 以 1,4-二氧六环 为溶剂， 以82%的产率得到
  参考文献：
  名称：

  Synthesis, CI-MS Analyses and Preliminary Biological Evaluation of a Novel Library of Hydrophobic Persulfide-Spacers α-Alkyl Glycosides

  摘要：

  We report the synthesis of novel polyether-based polyols derived from simple glycosides that bear sulfur spacers in the attempt to potentially provide new antibiotics. The CI-MS demonstrated the stepwise and successive fission of the sulfide-spacer groups; however, it does not distinguish between the alditols having different arrangement of O(CH2)(3)-S(CH2)(2)OH groups. The investigated compounds exhibited antimicrobial activities against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and antifungal activities against Candida albicans at a concentration of 1 mg / ml in DMF.

  DOI：

  10.2174/157017810790796372