3-(7-chloro-3-oxo-1H-isoindol-2-yl)oxane-2,6-dione | 1198299-67-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-(7-chloro-3-oxo-1H-isoindol-2-yl)oxane-2,6-dione
• CAS: 1198299-67-0
• 化学式: C₁₃H₁₀ClNO₄
• 分子量: 279.68
• InChiKey: CEJVKOGHWDPFKF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  63.7
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] METHODS FOR SYNTHESIZING 3-(SUBSTITUTED DIHYDROISOINDOLINONE-2-YL)-2,6-DIOXOPIPERIDINE, AND INTERMEDIATES THEREOF<br/>[FR] PROCÉDÉS POUR LA SYNTHÈSE DE 3-[(DIHYDROISOINDOLINONE SUBSTITUÉE)-2-YL]-2,6-DIOXOPIPÉRIDINE ET INTERMÉDIAIRES CORRESPONDANTS
  申请人：NANJING CAVENDISH BIO ENGINEERING TECHNOLOGY CO LTD

  公开号：WO2010139266A1

  公开（公告）日：2010-12-09

  The present invention discloses methods for synthesizing 3-(substituted dihydroisoindolinone-2-yl)-2,6-dioxopiperidine and intermediates thereof, namely, the synthesis of compounds of the Formula (I), with each substitutional group defined in the patent specification. Owing to the advantages of high productivity, little influence to the environment and material accessibility, the methods of the present invention is suitable for industrial production.

  本发明揭示了合成3-(取代二氢异吲哚酮-2-基)-2,6-二氧代哌啶及其中间体的方法，即合成式(I)化合物的方法，其中每个取代基固定在专利规范中定义。由于高生产率、对环境影响小和材料易得的优点，本发明的方法适用于工业生产。
• Methods for Synthesizing 3-(Substituted Dihydroisoindolinone-2-YL)-2, 6-Dioxopiperidine, and Intermediates Thereof
  申请人：Yan Rong

  公开号：US20120077982A1

  公开（公告）日：2012-03-29

  The present invention discloses methods for synthesizing 3-(substituted dihydroisoindolinone-2-yl)-2,6-dioxopiperidine and intermediates thereof, namely, the synthesis of compounds of the Formula (I), with each substitutional group defined in the patent specification. Owing to the advantages of high productivity, little influence to the environment and material accessibility, the methods of the present invention is suitable for industrial production.

  本发明揭示了一种合成3-(取代的二氢异吲哚酮-2-基)-2,6-二氧代哌啶及其中间体的方法，即合成式(I)化合物的方法，其中每个取代基在专利规范中有定义。由于高生产率、对环境影响小和材料易得的优点，本发明的方法适用于工业生产。
• Methods for synthesizing 3-(substituted dihydroisoindolinone-2-yl)-2, 6-dioxopiperidine, and intermediates thereof
  申请人：Yan Rong

  公开号：US20150284359A1

  公开（公告）日：2015-10-08

  The present invention discloses methods for synthesizing 3-(substituted dihydroisoindolinone-2-yl)-2,6-dioxopiperidine and intermediates thereof, namely, the synthesis of compounds of the Formula (I), with each substitutional group defined in the patent specification. Owing to the advantages of high productivity, little influence to the environment and material accessibility, the methods of the present invention is suitable for industrial production.

  本发明揭示了合成3-(取代的二氢异吲哚啉-2-基)-2,6-二氧代哌啶及其中间体的方法，即合成式（I）中每个取代基在专利规范中定义的化合物的方法。由于高产率、对环境影响小和物质可及性的优点，本发明的方法适用于工业生产。
• Methods for synthesizing 3-(Substituted Dihydroisoindolinone-2-YI)-2, 6-Dioxopiperidine, and intermediates thereof
  申请人：Yan Rong

  公开号：US20150284329A1

  公开（公告）日：2015-10-08

  The present invention discloses methods for synthesizing 3-(substituted dihydroisoindolinone-2-yl)-2,6-dioxopiperidine and intermediates thereof, namely, the synthesis of compounds of the Formula (I), with each substitutional group defined in the patent specification. Owing to the advantages of high productivity, little influence to the environment and material accessibility, the methods of the present invention is suitable for industrial production.

  本发明公开了一种合成3-(取代二氢异吲哚酮-2-基)-2,6-二氧代哌啶及其中间体的方法，即合成式(I)中每个取代基在专利规范中定义的化合物的合成方法。由于高产率、对环境影响小和材料易得等优点，本发明的方法适合工业生产。
• METHODS FOR SYNTHESIZING 3-(SUBSTITUTED DIHYDROISOINDOLINONE-2-YL)-2,6-DIOXOPIPERIDINE, AND INTERMEDIATES THEREOF
  申请人：Nanjing Cavendish Bio-Engineering Technology Co., Ltd.

  公开号：EP2438053B1

  公开（公告）日：2013-09-11