1-(5-methoxy-2-methyl-1(3)H-imidazol-4-yl)-ethanone | 56536-45-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(5-methoxy-2-methyl-1(3)H-imidazol-4-yl)-ethanone
• 英文别名: 1-(5-Methoxy-2-methyl-1H-imidazol-4-yl)ethanone；1-(4-methoxy-2-methyl-1H-imidazol-5-yl)ethanone
• CAS: 56536-45-9
• 化学式: C₇H₁₀N₂O₂
• 分子量: 154.169
• InChiKey: MVQJCRNVZXGZOQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  55
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• NOVEL FUSED IMIDAZOLE DERIVATIVE
  申请人：BANYU PHARMACEUTICAL CO., LTD.

  公开号：EP1813613A1

  公开（公告）日：2007-08-01

  The present invention relates to a compound represented by the Formula [I]: Wherein: the A ring is a 5-membered aromatic heterocyclic group containing at least one hetero atom selected from a nitrogen atom, and the like; A1 and A2, are each a nitrogen atom, and the like; X2, X3, X4, and X5 are all carbon atoms, or alternatively any one of X2, X3, X4, and X5 is a nitrogen atom and the rest are all carbon atoms; R1 is a hydrogen atom, or the like; R2, R3, R4, and R5, are each a hydrogen atom, or the like; R6 and R6', are each a hydrogen atom, and the like; R7 is an aryl group and the like; and R8 is an amino group or a hydroxy group, or a pharmaceutically acceptable salt or ester thereof.

  本发明涉及一种由式 [I] 表示的化合物： 其中 A环为5元芳香杂环基团，含有至少一个选自氮原子等的杂原子；A1和A2各自为氮原子等；X2、X3、X4和X5均为碳原子，或者X2、X3、X4和X5中的任一个为氮原子，其余均为碳原子；R1是氢原子或类似物；R2、R3、R4和R5各自是氢原子或类似物；R6和R6'各自是氢原子或类似物；R7是芳基或类似物；R8是氨基或羟基、 或其药学上可接受的盐或酯。
• Novel Fused Imidazole Derivative
  申请人：Sato Yoshiyuki

  公开号：US20080103136A1

  公开（公告）日：2008-05-01

  The present invention relates to a compound represented by the Formula [I]: Wherein: the A ring is a 5-membered aromatic heterocyclic group containing at least one hetero atom selected from a nitrogen atom, and the like; A 1 and A 2 , are each a nitrogen atom, and the like; X 2 , X 3 , X 4 , and X 5 are all carbon atoms, or alternatively any one of X 2 , X 3 , X 4 , and X 5 is a nitrogen atom and the rest are all carbon atoms; R 1 is a hydrogen atom, or the like; R 2 , R 3 , R 4 , and R 5 , are each a hydrogen atom, or the like; R 6 and R 6 ′, are each a hydrogen atom, and the like; R 7 is an aryl group and the like; and R 8 is an amino group or a hydroxy group, or a pharmaceutically acceptable salt or ester thereof.
• US8030327B2
  申请人：——

  公开号：US8030327B2

  公开（公告）日：2011-10-04