| 1417352-96-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1417352-96-5
• 化学式: C₁₀₇H₁₀₆Cl₃NO₂₇
• 分子量: 1944.37
• InChiKey: GUQDSFRUWWDTFN-WTIRVYMESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  16.61
• 重原子数：
  138.0
• 可旋转键数：
  43.0
• 环数：
  15.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  308.28
• 氢给体数：
  1.0
• 氢受体数：
  27.0

反应信息

• 作为反应物：
  描述：

  在 palladium 10% on activated carbon 、 氢气 作用下， 以 甲醇 为溶剂， 生成
  参考文献：
  名称：

  Synthesis of an antimetastatic tetrasaccharide β-d-Gal-(1→4)-β-d-GlcpNAc-(1→6)-α-d-Manp-(1→6)-β-d-Manp-OMe

  摘要：

  An antimetastatic tetrasaccharide T-1, beta-D-Gal-(1 -> 4)-beta-D-GlcpNAc-(1 -> 6)-alpha-D-Manp-(1 -> 6)-beta-D-Manp-OMe, was synthesized with two approaches. The first approach was a conventional method employing thioglycoside and Koenigs-Knorr glycosylation reaction in 24% overall yield. The second one was a novel route through the azidoiodo-glycosylation strategy by using 2-iodo-2-deoxylactosyl azide as the donor in 36% overall yield. (C) 2012 Zhong Jun Li. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2012.10.022
• 作为产物：
  描述：

  、 C₅₅H₆₀O₁₁ 在 silver trifluoromethanesulfonate 作用下， 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Synthesis of an antimetastatic tetrasaccharide β-d-Gal-(1→4)-β-d-GlcpNAc-(1→6)-α-d-Manp-(1→6)-β-d-Manp-OMe

  摘要：

  An antimetastatic tetrasaccharide T-1, beta-D-Gal-(1 -> 4)-beta-D-GlcpNAc-(1 -> 6)-alpha-D-Manp-(1 -> 6)-beta-D-Manp-OMe, was synthesized with two approaches. The first approach was a conventional method employing thioglycoside and Koenigs-Knorr glycosylation reaction in 24% overall yield. The second one was a novel route through the azidoiodo-glycosylation strategy by using 2-iodo-2-deoxylactosyl azide as the donor in 36% overall yield. (C) 2012 Zhong Jun Li. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2012.10.022