1-(1-benzyl-4-(3,4-dimethoxyphenyl)-2-methyl-1H-pyrrol-3-yl)ethanone | 1429632-58-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 1-(1-benzyl-4-(3,4-dimethoxyphenyl)-2-methyl-1H-pyrrol-3-yl)ethanone
• CAS: 1429632-58-5
• 化学式: C₂₂H₂₃NO₃
• 分子量: 349.43
• InChiKey: NGACGDOQZNRZHO-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  硝基甲烷 、 3,4-二甲氧基苯甲醛 、 乙酰丙酮 、 苄胺 在 1-n-butylimidazolium tetrafluoroborate 作用下， 反应 0.84h， 以86%的产率得到  1-(1-benzyl-4-(3,4-dimethoxyphenyl)-2-methyl-1H-pyrrol-3-yl)ethanone
  参考文献：
  名称：

  Catalyst-free four-component protocol for the synthesis of substituted pyrroles under reusable reaction media

  摘要：

  An efficient four-component protocol is described for the synthesis of diversely functionalized pyrroles under catalyst-free condition by using ionic liquid as a reaction media. The developed method is mild, high yielding, and amenable for a variety of amines as well as aldehydes. Moreover the procedure is of environmentally benign nature in which ionic liquid 1-n-butylimidazolium tetrafluoroborate [Hbim]BF4 is used as a reusable and efficient reaction medium without using any additional catalyst or promoter. (C) 2013 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2013.01.098