4-Isopentyl-4H-1,2,4-triazol | 27106-43-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-Isopentyl-4H-1,2,4-triazol
• 英文别名: 4-(3-methyl-butyl)-4H-[1,2,4]triazole；4-(3-methylbutyl)-4H-1,2,4-triazole；4-(3-methylbutyl)-1,2,4-triazole
• CAS: 27106-43-0
• 化学式: C₇H₁₃N₃
• 分子量: 139.2
• InChiKey: HZPVEBWUHGUQLU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.32
• 重原子数：
  10.0
• 可旋转键数：
  3.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  30.71
• 氢给体数：
  0.0
• 氢受体数：
  3.0

文献信息

• BENZAZEPIN-2(1H)-ONE DERIVATIVES
  申请人：Boyle Jessica

  公开号：US20080267942A1

  公开（公告）日：2008-10-30

  Compounds of formula (I) and pharmaceutically acceptable salts thereof are agonists at the beta-2 adrenoceptor. They are useful as feed additives for livestock animals.

  式(I)化合物及其药学上可接受的盐是β-2肾上腺素受体的激动剂。它们可用作家畜饲料添加剂。
• INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF DIACYLGLYCERIDE O-ACYLTRANSFERASE 2
  申请人：Shen Dong-Ming

  公开号：US20190330239A1

  公开（公告）日：2019-10-31

  The present invention relates to a compound represented by formula I′: and pharmaceutically acceptable salts thereof. The compounds of formula I are inhibitors of diacylglyceride O-acyltransferase 2 (“DGAT2”) and may be useful in the treatment, prevention and suppression of diseases mediated by DGAT2. The compounds of the present invention may be useful in the treatment of hepatic steatosis, diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, cardiorenal diseases such as chronic kidney diseases and heart failure and related diseases and conditions.
• US4120864A
  申请人：——

  公开号：US4120864A

  公开（公告）日：1978-10-17
• US4271308A
  申请人：——

  公开号：US4271308A

  公开（公告）日：1981-06-02