dimethyl 2,2-bis(1-methyl-1H-indol-3-yl)butanedioate | 36132-26-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: dimethyl 2,2-bis(1-methyl-1H-indol-3-yl)butanedioate
• 英文别名: Dimethyl α,α-bis-(1-methylindol-3-yl)-succinat；2,2-bis-(1-methyl-indol-3-yl)-succinic acid dimethyl ester
• CAS: 36132-26-0
• 化学式: C₂₄H₂₄N₂O₄
• 分子量: 404.466
• InChiKey: MWRNSOBDAXBRDT-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  1-甲基吲哚 、 丁炔二酸二甲酯 在 K-10 montmorillonite 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 3.0h， 以57%的产率得到dimethyl 2,2-bis(1-methyl-1H-indol-3-yl)butanedioate
  参考文献：
  名称：

  在K10蒙脱土存在下吲哚生物碱与α，β-不饱和羰基化合物的亲电取代反应

  摘要：

  Reactions of indole, 1-methylindole, and 3-methylindole with dimethyl acetylenedicarboxylate in the presence of K10 montmorillonite as a catalyst led to the formation of the corresponding dimethyl 2,2-bis(indolyl)butanedioates. The reaction of 2-methylindole with dimethyl acetylenedicarboxylate gave dimethyl 2-(2-methyl-1H-indol-3-yl)maleate and dimethyl 2-methyl-1H-1-benzoazepine-3,,4-dicarboxylate. Dimethyl 1,5-dimethyl-1H-1-benzoazepine-3,4-dicarboxylate was obtained by treatment of 1,3-dimethylindole with dimethyl acetylenedicarboxylate using K 10 clay as a catalyst.

  DOI：

  10.1134/s107042800606011x