N-(Propan-2-yl)-1,3-thiazole-4-carboxamide | 105611-05-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-(Propan-2-yl)-1,3-thiazole-4-carboxamide
• 英文别名: N-propan-2-yl-1,3-thiazole-4-carboxamide
• CAS: 105611-05-0
• 化学式: C₇H₁₀N₂OS
• 分子量: 170.23
• InChiKey: RGKWQHHIWOGIPT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  70.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHSAFT

  公开号：US20180016273A1

  公开（公告）日：2018-01-18

  The invention relates to novel compounds of the formula (I) in which the R 1 , R 2a , R 2b , R 3 , A 1 , A 2 , A 4 and n have the meanings given above, to their usee as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for their preparation.

  本发明涉及到式(I)的新型化合物，其中R1，R2a，R2b，R3，A1，A2，A4和n具有上述所给出的含义，以及它们作为杀虫剂和/或杀虫剂用于控制动物害虫的用途，以及它们制备的过程和中间体。
• SUBSTITUTED PHENYLAMINE CARBOXAMIDE ANALOGS AS MGLUR5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME
  申请人：Conn P. Jeffrey

  公开号：US20110166158A1

  公开（公告）日：2011-07-07

  Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本发明涉及代谢型谷氨酸受体亚型5（mGluR5）的负向变构调节剂；制备该化合物的合成方法；包含该化合物的药物组合物；以及使用该化合物和组合物治疗与谷氨酸功能障碍相关的神经和精神障碍的方法。该摘要旨在作为搜索特定领域的扫描工具，不限制本发明。
• HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS
  申请人：Berger Richard

  公开号：US20110028461A1

  公开（公告）日：2011-02-03

  The present invention provides compounds of Formula I, pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.

  本发明提供了I式化合物，其药物组成物以及使用该组成物的方法，用于治疗或预防通过激活β3肾上腺素受体介导的疾病。
• 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHAFT

  公开号：US10654845B2

  公开（公告）日：2020-05-19

  The invention relates to novel compounds of the formula (I) in which the R1, R2a, R2b, R3, A1, A2, A4 and n have the meanings given above, to their use as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for their preparation.

  本发明涉及式 (I) 的新型化合物 其中 R1、R2a、R2b、R3、A1、A2、A4 和 n 具有上述含义，涉及它们作为控制动物害虫的杀螨剂和/或杀虫剂的用途，以及制备它们的工艺和中间体。
• US8501757B2
  申请人：——

  公开号：US8501757B2

  公开（公告）日：2013-08-06