4-(trimethylammonio)butane-1-sulfonate | 22442-92-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 4-(trimethylammonio)butane-1-sulfonate
• 英文别名: SO3-btma；4-(Trimethylammonium)-butylsultan；4-Trimethylammonium-butan-sulfonat-(1)；4-(trimethylazaniumyl)butane-1-sulfonate
• CAS: 22442-92-8
• 化学式: C₇H₁₇NO₃S
• 分子量: 195.283
• InChiKey: VEIOYKCZLYJNRD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  65.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(trimethylammonio)butane-1-sulfonate 在 硫酸 作用下， 生成 N,N,N-trimethyl-N-sulfobutyl hydrosulfate
  参考文献：
  名称：

  Efficient One-Pot Synthesis of 2-Alkylquinolines under Solvent-Free Conditions Using Sulfonic Acid Functionalized Ionic Liquid as a Recoverable and Reusable Catalyst

  摘要：

  Sulfonic acid functionalized ionic liquid (FIL-A) was firstly used as a recoverable and reusable catalyst for the synthesis of 2-alkylquinoline derivatives from simple and readily available alkylaldehydes and arylamines. The method has the advantages of simple experimental procedure, easy recovery and reuse of catalyst, solvent-free and mild reaction conditions, excellent functional group tolerance, etc. which makes it a highly practical and environmentally benign pathway for the synthesis of 2-alkylquinolines.

  DOI：

  10.3987/com-11-12289
• 作为产物：
  描述：

  1,4-丁磺酸内酯 、 三甲胺 反应 10.0h， 生成 4-(trimethylammonio)butane-1-sulfonate
  参考文献：
  名称：

  Direct Hydroxylation of p-Xylene to 2,5-Xylenol with Hydroxylamine in Ionic Liquids/Molybdenum Catalytic System

  摘要：

  在离子液体/钼催化系统中，使用氢氧胺直接对对二甲苯进行氢氧化反应生成2,5-二甲醇。该催化系统中可以实现高达80-98%的2,5-二甲醇选择性，以及良好的对二甲苯转化率（5.9-9.9%）。回收实验表明，离子液体/钼催化系统具有足够的稳定性，可以重复用于氢氧化反应。

  DOI：

  10.14233/ajchem.2014.16742

文献信息

• Alkylating agents containing a quaternary nitrogen group
  作者：Peter Blumbergs、Arthur B. Ash、F. A. Daniher、Calvin Lee Stevens、H. O. Michel、B. E. Hackley、J. Epstein

  DOI：10.1021/jo01264a067

  日期：1969.12
• Helferich,B.; Boellert,V., Justus Liebigs Annalen der Chemie, 1961, vol. 647, p. 37 - 40
  作者：Helferich,B.、Boellert,V.

  DOI：——

  日期：——
• US9850265B2
  申请人：——

  公开号：US9850265B2

  公开（公告）日：2017-12-26
• Efficient One-Pot Synthesis of 2-Alkylquinolines under Solvent-Free Conditions Using Sulfonic Acid Functionalized Ionic Liquid as a Recoverable and Reusable Catalyst
  作者：Min Zhang、Yuqiang Ding、Biao Xiong、Ting Wang、Li Wang

  DOI：10.3987/com-11-12289

  日期：——

  Sulfonic acid functionalized ionic liquid (FIL-A) was firstly used as a recoverable and reusable catalyst for the synthesis of 2-alkylquinoline derivatives from simple and readily available alkylaldehydes and arylamines. The method has the advantages of simple experimental procedure, easy recovery and reuse of catalyst, solvent-free and mild reaction conditions, excellent functional group tolerance, etc. which makes it a highly practical and environmentally benign pathway for the synthesis of 2-alkylquinolines.
• Direct Hydroxylation of p-Xylene to 2,5-Xylenol with Hydroxylamine in Ionic Liquids/Molybdenum Catalytic System
  作者：D. Zhang、L. Gao、C. Jin、W. Xue、X. Zhao、S. Wang、Y. Wang

  DOI：10.14233/ajchem.2014.16742

  日期：——

  Direct hydroxylation of p-xylene to 2,5-xylenol with hydroxylamine was carried out in an ionic liquids/molybdenum catalytic system. High 2,5-xylenol selectivity (80-98 %) can be achieved with good p-xylene conversion (5.9-9.9 %) in this catalytic system. The recycling experiments suggested the ionic liquids/molybdenum catalytic system was stable enough to be recycled for the hydroxylation reaction.

  在离子液体/钼催化系统中，使用氢氧胺直接对对二甲苯进行氢氧化反应生成2,5-二甲醇。该催化系统中可以实现高达80-98%的2,5-二甲醇选择性，以及良好的对二甲苯转化率（5.9-9.9%）。回收实验表明，离子液体/钼催化系统具有足够的稳定性，可以重复用于氢氧化反应。