3-Dodecanoylamino-N-dodecyl-succinamic acid | 177600-92-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-Dodecanoylamino-N-dodecyl-succinamic acid
• CAS: 177600-92-9
• 化学式: C₂₈H₅₄N₂O₄
• 分子量: 482.748
• InChiKey: GSYKKKICSWPTNF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  34.0
• 可旋转键数：
  25.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  95.5
• 氢给体数：
  3.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  3-Dodecanoylamino-N-dodecyl-succinamic acid 在 4-二甲氨基吡啶 、 (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate 、 溶剂黄146 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 6.0h， 生成
  参考文献：
  名称：

  Synthesis of double-chain glycolipids derived from aspartic acid : Preliminary investigation of their colloidal behavior

  摘要：

  Double-tailed glycolipids derived from mono-, di- and tri-O-galactosyl tris-(hydroxymethyl) aminomethane and aspartic acid have been synthesized. Preliminary assessment by negative staining transmission electron microscopy of dispersions of these amphiphiles showed the formation of either vesicles, helical structures or fibers depending on the glycolipid structure.

  DOI：

  10.1016/s0040-4039(00)76654-8
• 作为产物：
  描述：

  在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 反应 12.0h， 以98%的产率得到3-Dodecanoylamino-N-dodecyl-succinamic acid
  参考文献：
  名称：

  Synthesis of double-chain glycolipids derived from aspartic acid : Preliminary investigation of their colloidal behavior

  摘要：

  Double-tailed glycolipids derived from mono-, di- and tri-O-galactosyl tris-(hydroxymethyl) aminomethane and aspartic acid have been synthesized. Preliminary assessment by negative staining transmission electron microscopy of dispersions of these amphiphiles showed the formation of either vesicles, helical structures or fibers depending on the glycolipid structure.

  DOI：

  10.1016/s0040-4039(00)76654-8