(E)-(3-butoxybut-1-en-1-yl)benzene | 100863-02-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-(3-butoxybut-1-en-1-yl)benzene
• 英文别名: [(E)-3-butoxybut-1-enyl]benzene
• CAS: 100863-02-3
• 化学式: C₁₄H₂₀O
• 分子量: 204.312
• InChiKey: TZGNIVQTXFXNKR-ZHACJKMWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  苯甲醛 在 bis-triphenylphosphine-palladium(II) chloride 、 silver(I) acetate 、 sodium hydride 、 氯甲基甲基醚 、 三苯基膦 作用下， 以 四氢呋喃 、 乙腈 为溶剂， 反应 36.25h， 生成 (E)-(3-butoxybut-1-en-1-yl)benzene
  参考文献：
  名称：

  钯催化 1-芳基丁二烯的区域选择性分子间氢化烷氧基化

  摘要：

  开发了一种通过 Pd 催化 1-芳基丁二烯区域选择性分子间加氢烷氧基化合成( E )-(3-烷氧基丁-1-烯基)苯的有效方法。该方法操作简单，无需干反应条件，并且对多种底物具有耐受性。发现氯甲基甲基醚（MOMCl）作为添加剂对于反应的成功至关重要。

  DOI：

  10.1021/acs.joc.2c01252

文献信息

• Nickel-Catalyzed Denitrated Coupling Reaction of Nitroalkenes with Aliphatic and Aromatic Alkenes
  作者：Na Zhang、Zheng-Jun Quan、Xi-Cun Wang

  DOI：10.1002/adsc.201600586

  日期：2016.10.20

  A simple and practical denitrated coupling reaction of nitroalkenes with various alkenes using a nickel catalyst and triethoxysilane [(EtO)3SiH] as reducing agent was achieved. Under mild reaction conditions, both aliphatic and aromatic alkenes could react with nitroalkenes to obtain a series of olefins with different functional groups in satisfactory yields under an air atmosphere, which were previously

  使用镍催化剂和三乙氧基硅烷[（EtO）3 SiH]作为还原剂，实现了硝基烯烃与各种烯烃的简单实用的脱硝偶联反应。在温和的反应条件下，脂肪族和芳香族烯烃都可以与硝基烯烃反应，从而在空气气氛下以令人满意的收率获得一系列具有不同官能团的烯烃，这以前是很难或不可能获得的。
• A novel palladium-catalyzed hydroalkoxylation of alkenes with a migration of double bond
  作者：Jiajing Tan、Zuhui Zhang、Zhiyong Wang

  DOI：10.1039/b800838h

  日期：——

  A novel palladium-catalyzed addition of alcohols to olefins was developed, in which a migration of double bond was involved. By this new method, a variety of allylic ethers were prepared with moderate to high yields under mild conditions.

  开发了一种新型的钯催化的醇加成烯烃，其中涉及双键的迁移。通过这种新方法，在温和条件下以中等至高收率制备了各种烯丙基醚。
• Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel bronsted acid catalysts
  申请人：The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Las Vegas

  公开号：US11248014B2

  公开（公告）日：2022-02-15

  Provided herein are diaryl and arylalkyl phosphonates, useful as intermediates in, for example, the synthesis of leukocyte elastase inhibitors, potassium channel modulators, chemiluminescence materials, and flame retardants, and methods for making same. Also provided are N-heterocyclic phosphorodiamidic acids (NHPAs) useful in reactions such as, for example, in the preparation of diaryl and arylalkyl phosphonates. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本文提供的是二芳基和芳烷基膦酸盐，可用作例如合成白细胞弹性蛋白酶抑制剂、钾通道调节剂、化学发光材料和阻燃剂的中间体，以及制造方法。此外，还提供了在制备二芳基和芳基烷基膦酸盐等反应中有用的 N-杂环磷酸二酰胺（NHPA）。本摘要旨在作为一种扫描工具，用于特定技术领域的搜索，并不限制本发明。
• Pansewitsch-Koljada; Bogusch, Zhurnal Obshchei Khimii, 1959, vol. 29, p. 1198,1199; engl. Ausg. S. 1168, 1169
  作者：Pansewitsch-Koljada、Bogusch

  DOI：——

  日期：——
• CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS
  申请人：The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada

  公开号：US20210147457A1

  公开（公告）日：2021-05-20

  Provided herein are diaryl and arylalkyl phosphonates, useful as intermediates in, for example, the synthesis of leukocyte elastase inhibitors, potassium channel modulators, chemiluminescence materials, and flame retardants, and methods for making same. Also provided are N-heterocyclic phosphorodiamidic acids (NHPAs) useful in reactions such as, for example, in the preparation of diaryl and arylalkyl phosphonates. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.