strontium bis(hexamethyldisilylamide)bis(tetrahydrofuran) | 133766-06-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧唑烯
• 英文名称: strontium bis(hexamethyldisilylamide)bis(tetrahydrofuran)
• 英文别名: bis(tetrahydrofuran)strontium di(bis(trimethylsilyl)amide)；Sr[N(SiMe3)2](THF)2；Sr[N(SiMe3)2]2(THF)2；strontium bis(hexamethyldisilazane)bis(tetrahydrofuran)
• CAS: 133766-06-0
• 化学式: 2C₄H₈O*2C₆H₁₈NSi₂*Sr
• 分子量: 552.607
• InChiKey: ASKWOQRAPPUQCC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.45
• 重原子数：
  15.0
• 可旋转键数：
  2.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  23.33
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  N,N'-bis(trimethylsilyl)sulfurdiimide 、 strontium bis(hexamethyldisilylamide)bis(tetrahydrofuran) 以 四氢呋喃 、 甲苯 为溶剂， 反应 2.0h， 以84%的产率得到strontium bis[N,N,N'N''-tetrakis(trimethylsilyl)triazasulphite] tetrahydrofuran
  参考文献：
  名称：

  Synthesis and structure of alkaline earth metal diazasulphinates and triazasulphites1Dedicated to Professor Ken Wade, the protagonist of boron chemistry and mentor of Main Group chemistry, on the occasion of his 65th birthday.1

  摘要：

  The syntheses and solid state structures of (THF2M{(NSiMe3)(2)SPh}(2)] (M=Ca, 1; M=Sr, 2; M=Ba 3) and (THFnM{(NSiMe3)(2)SN(SiMe3)(2)}(2)] (M = Mg, n = 0, 4; M = Sr, n = 1, 5) are presented. Although the (Me3Si)(2)NS(NSiMe3)(2)(-) anion resembles to a large extent the structural features of the PhS(NSiMe3)(2)(-) anion, careful examination of structural parameters reveals marginal differences in their coordination to alkaline earth metal dications. Above all, bonding to the metals is predominantly ionic, but the nature of the small covalent contribution differs in both anionic systems. Strictly planar SN2M four-membered rings in 1, 2 and 3 indicate exclusively sigma-bonding of the PhS(Me3SiN)(2)(-) anion towards the alkaline earth metal. The SN2 moiety of the (Me3Si)(2)NS(NSiMe3)(2)(-) anion seems to be more pi electron rich. The metal is not located in the plane of the N-S-N chelating ligand, but is displaced from the plane towards the sulphur atom to interact with the pi electron density. This effect is caused neither by the steric demand of the ligand nor by packing effects but is induced by the different electronic nature of the ligand. Structural comparisons to related systems substantiate these findings. The size and polarizability of barium, in particular, enables this metal to interact with the non-directed pi electron density of the SN2 fragment. (C) 1998 Elsevier Science S.A.

  DOI：

  10.1016/s0022-328x(97)00187-3
• 作为产物：
  描述：

  四氢呋喃 、 双(三甲基硅烷基)氨基钾 在 strontium p-toluenesulfonate 作用下， 反应 4.0h， 以82%的产率得到strontium bis(hexamethyldisilylamide)bis(tetrahydrofuran)
  参考文献：
  名称：

  Alkaline-earth-metal arenesulfonates as precursors to organic derivatives of Group 2 metals

  摘要：

  对易得的碱金属芳烃磺酸盐 M(OSO2R)2（由 MCO3 和 2RSO3H 反应得到）与一系列锂、钠或钾有机化合物在四氢呋喃（THF）中处理，获得了相应的碱金属有机化合物，并且产率很高，包括新化合物 LiM(OSO2R)2[CH(SiMe3)2](THF) 和 KM[CH(SiMe3)2]3(THF)3（M = Ca、Sr 或 Ba；R = C6H4Me-4、C6H2Me3-2,4,6 或 C6H4But-4）。

  DOI：

  10.1039/dt9960004151
• 作为试剂：
  描述：

  苯乙炔 、 N,N'-二环己基碳二亚胺 在 strontium bis(hexamethyldisilylamide)bis(tetrahydrofuran) 作用下， 以 氘代四氢呋喃 、 氘代苯 为溶剂， 反应 18.0h， 生成 N,N'-dicyclohexyl-3-phenylpropiolamidine
  参考文献：
  名称：

  Alkaline earth catalysis for the 100% atom-efficient three component assembly of imidazolidin-2-ones

  摘要：

  可以使用非毒性和成本效益高的碱土金属双(酰胺)预催化剂在非常温和的反应条件下合成多种官能化咪唑啉-2-酮，这是一种100%原子效率的、分子间一锅法组装，使用廉价的炔烃和累积烯试剂。

  DOI：

  10.1039/c4cc05223d

文献信息

• Group 2 metal (Mg, Ca, Sr) silylamides supported by a cyclen-derived macrocyclic polyamine
  作者：Debabrata Mukherjee、Satoru Shirase、Klaus Beckerle、Thomas P. Spaniol、Kazushi Mashima、Jun Okuda

  DOI：10.1039/c7dt01727h

  日期：——

  Heteroleptic bis(silyl)amides of magnesium and calcium [(L)MN(SiMe3)2}] [M = Mg, Ca; LH = 1,4,7-trimethyl-1,4,7,10-tetraazacyclododecane; (Me3TACD)H] were previously synthesized from LH and [MN(SiMe3)2}2]. Strontium bis(silyl)amides [SrN(SiMe3)2}2(thf)2] and [SrN(SiHMe2)2}2(thf)2/3] reacted with LH to give different types of products, depending on the presence of the beta-SiH function. While the

  镁和钙的[[L] M N（SiMe3）2}的多官能双（甲硅烷基）酰胺] [M = Mg，Ca; LH ＝ 1,4,7-三甲基-1,4,7,10-四氮杂环十二烷；（Me3TACD）H]是先前从LH和[M N（SiMe3）2} 2]合成的。双（甲硅烷基）酰胺锶[Sr N（SiMe3）2} 2（thf）2]和[Sr N（SiHMe2）2} 2（thf）2/3]与LH反应生成不同类型的产物，具体取决于β-SiH功能的存在。前者进行质子分解以提供酰胺桥联的二聚体[（L）Sr N（SiMe3）2}] 2（1），后者进行加合物[（LH）Sr N（SiHMe2）2} 2]（ 2）为稳定固体。2在溶液中缓慢进行分子内Si-H / HN脱氢偶联，通过释放H2得到[（L）SiMe2N（SiHMe2）} Sr N（SiHMe2）2}]（3）。HN（SiHMe2）2转氨1的结果取决于相对化学计量比。A
• Lipophilic strontium and calcium alkyls, amides and phenoxides; X-ray structures of the crystalline square-planar [{trans-Sr(NR′₂)₂(µ-1,4-dioxane)}∞] and tetrahedral [CaR₂(1,4-dioxane)₂]; R′= SiMe₃, R = CH(SiMe₃)₂]
  作者：F. Geoffrey N. Cloke、Peter B. Hitchcock、Michael F. Lappert、Gerard A. Lawless、Beatriz Royo

  DOI：10.1039/c39910000724

  日期：——

  Treatment of pyrophoric strontium powder in tetrahydrofuran with ArOH (Ar = C6H2But3-2,4,6) or HNR′2 at ambient temperature affords crystalline [Sr(OAr)2(THF)4] or [Sr(NR′2)2(THF)2]3, respectively, and 3 with 1,4-dioxane yields crystalline [trans-Sr(NR′2)2(µ-1,4-dioxane)}∞]4; co-condensation of calcium vapour and RBr in THF at 77 K affords [CaR2(THF)3]5, which with 1,4-dioxane gives [CaR2(1,4-dioxane)2]6; X-ray structures reveal the alkaline earth metal environment to be square-planar for 4[Sr-N 2.449(7), Sr-O 2.533(9)Å] but tetrahedral for 6[Ca-C 2.483(5), Ca-O 2.373(4)Å] with dioxane as a bridging bidentate 4 or monodentate 6 ligand.

  在室温下，使用ArOH（Ar = C6H2But3-2,4,6）或HNR₂₂处理四氢呋喃中的自燃性锶粉，分别得到晶体[Sr(OAr)₂(THF)₄]或[Sr(NR₂₂)₂(THF)₂]₃，而与1,4-二恶烷反应则得到晶体[trans-Sr(NR₂₂)₂(μ-1,4-二恶烷)}⁴]；在77 K下，将钙蒸气与RBr在THF中共凝聚得到[CaR₂(THF)₃]₅，后者与1,4-二恶烷反应得到[CaR₂(1,4-二恶烷)₂]₆；X射线结构分析显示，碱土金属环境对于₄[Sr-N 2.449(7), Sr-O 2.533(9) Å]为平面正方形，而对于₆[Ca-C 2.483(5), Ca-O 2.373(4) Å]则为四面体，其中二恶烷作为桥连双齿₄或单齿₆配体。
• Tetranuclear Strontium and Barium Siloxide/Amide Clusters in Metal‐Ligand Cooperative Catalysis
  作者：Benjamin Freitag、Phillip Stegner、Katharina Thum、Christian A. Fischer、Sjoerd Harder

  DOI：10.1002/ejic.201800231

  日期：2018.5.15

  One‐pot reaction of 2,6‐iPr2‐aniline (DIPP‐NH2) with (Me2SiO)3 and Sr[N(SiMe3)2]2 (SrN′′2) gave a tetranuclear cluster consisting of four dianions [OSiMe2N‐DIPP]2– and four Sr2+ ions solvated each by one THF ligand. The general applicability of this method was investigated by variation of amine and metal. Anilines with smaller substituents led to insoluble uncharacterized coordination polymers, whereas

  的一锅反应-2,6-我镨2 -苯胺（DIPP-NH 2）与（ME 2的SiO）3和Sr [N（森达3）2 ] 2（SRN'' 2 ）得到由以下组成的四核簇四个阴离子[OSiMe 2 N-DIPP] 2–和四个Sr 2+离子各自被一个THF配体溶剂化。通过胺和金属的变化研究了该方法的一般适用性。具有较小取代基的苯胺导致不溶的未表征的配位聚合物，而体积较大的苯胺产生了无法纯化的可溶性产物混合物。伯烷基胺均未产生可分离的产物。在DIPP‐NH 2的对位引入t Bu基团然而，给出了具有增加的溶解度的同构簇。用钡可以获得类似的簇。发现Sr和Ba簇均是用于多种转化的活性催化剂：分子内烯烃加氢胺化，烯烃疏水化，吡啶硼氢化，吡啶氢化硅烷化和烯烃氢化硅烷化。Ba催化剂通常比Sr催化剂更具活性。对位的t Bu取代基也具有加速作用，这可能是由于溶解度提高所致。
• Discrete, Solvent-Free Alkaline-Earth Metal Cations: Metal···Fluorine Interactions and ROP Catalytic Activity
  作者：Yann Sarazin、Bo Liu、Thierry Roisnel、Laurent Maron、Jean-François Carpentier

  DOI：10.1021/ja2024977

  日期：2011.6.15

  [LO(3)}M](+)[X](-) (M = Zn, 8; Mg, 9; Ca, 10; Sr, 11; Ba, 12) and [RO(3)}M](+)[X](-) (M = Zn, 13; Mg, 14; Ca, 15; Sr, 16; Ba, 17) were synthesized in high yields (70-90%) by reaction of 3 or 4 with the neutral precursors M[N(SiMe(3))(2)](2)(THF)(x) (M = Zn, Mg, x = 0; M = Ca, Sr, Ba, x = 2). All compounds were fully characterized by spectroscopic methods, and the solid-sate structures of compounds 1, 3, 7, 8, 13

  已经设计了用于合成大碱土 (Ae) 金属 (Ca、Sr、Ba) 及其较小的 Zn 和 Mg 类似物的明确、无溶剂阳离子的有效协议。2,4-二叔丁基-6-(吗啉甲基)苯酚(LO(1)}H), 2-[双(2-甲氧基乙基)氨基]甲基}-4,6-二-叔丁基苯酚 (LO(2)}H), 2-[(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)methyl]-4,6-di-tert-butylphenol (LO (3)}H) 和 2-[(1,4,7,10-tetraoxa-13-azacyclo-pentadecan-13-yl)methyl]-1,1,1,3,3,3-hexafluoropropan-2 -ol (RO(3)}H) 与 [H(OEt(2))(2)](+)[H(2)NB(C(6)F(5))(3)}( 2)](-) 很容易得到双酸性前配体
• Deprotonation of μ ₃ ‐Methylidyne Groups on a Ti ₃ O ₃ Support: A Way to Build Oxotitanocubanes Containing Alkali and Alkaline‐Earth Metals
  作者：Avelino Martín、Miguel Mena、María del Carmen Morales‐Varela、Cristina Santamaría

  DOI：10.1002/ejic.200300840

  日期：2004.5

  [TiCp*(µ-O)}3(µ3-CH)] (1) (Cp* = η5-C5Me5) was deprotonated by amides of the group 1 elements, [MN(SiMe3)2] (M = Li, Na, K, Rb, Cs) to form the oxoheterometallocubane complexes [M(μ3-O)3Ti3Cp*3(μ3-C)}] [M = Li (3), Na (4), K (5), Rb (6), Cs (7)]. Similar treatments of 1 with the alkaline-earth amides [MN(SiMe3)2}2(thf)2] (M = Mg, Ca, Sr) afforded the heterometallocubane derivatives [(thf)x(Me3Si)2N

  复合物 [TiCp*(µ-O)}3(µ3-CH)] (1) (Cp* = η5-C5Me5) 的 μ3-methylidyne 基团被 1 族元素的酰胺去质子化，[MN(SiMe3 )2] (M = Li, Na, K, Rb, Cs) 形成氧杂金属立方烷配合物 [M(μ3-O)3Ti3Cp*3(μ3-C)}] [M = Li (3), Na ( 4), K (5), Rb (6), Cs (7)]。用碱土酰胺 [MN(SiMe3)2}2(thf)2] (M = Mg, Ca, Sr) 对 1 进行类似处理，得到杂金属立方烷衍生物 [(thf)x(Me3Si)2NM}( μ3-O)3Ti3Cp*3(μ3-C)}] [M = Mg, x = 0, (8); Ca, x = 1, (9); Sr, x = 1, (10)] 高产率。将配体如环戊二烯 (C5H6) 或五甲基环戊二烯 (C5Me5H)