3-Ethyl-5-trichlormethyl-1,2,4-oxadiazol | 1196-99-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3-Ethyl-5-trichlormethyl-1,2,4-oxadiazol
• 英文别名: 5-Trichlormethyl-3-aethyl-1,2,4-oxadiazol；3-ethyl-5-trichloromethyl-[1,2,4]oxadiazole；3-Ethyl-5-(trichloromethyl)-1,2,4-oxadiazole
• CAS: 1196-99-2
• 化学式: C₅H₅Cl₃N₂O
• mdl: MFCD18838674
• 分子量: 215.466
• InChiKey: OPWLXADFMKMURJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  38.9
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• 4-(3,3-DIHALO-ALLYLOXY)PHENOL DERIVATIVES HAVING PESTICIDAL PROPERTIES
  申请人：Zambach Werner

  公开号：US20100016383A1

  公开（公告）日：2010-01-21

  Compounds of formula wherein A 0 is a bond or a C 1 -C 6 alkylene bridge; A 1 , A 2 and A 3 are a C 1 -C 6 alkylene bridge; D is CH or N; W is, for example, O, S, SO, SO 2 , —C(═O)—O— or —O—C(═O)—; T is a bond or, for example, O, NH, S, SO or SR 2 ; Q is, for example, O, S, SO or SO 2 ; Y is, for example, O, S, SO or SO 2 ; X 1 and X 2 are each independently of the other fluorine, chlorine or bromine; R 1 , R 2 and R 3 are, for example, H, halogen, OH, SH, CN or nitro; R 4 is, for example, H, halogen, OH, SH, CN, nitro or C 1 -C 6 alkyl; R 5 is, for example, H, CN, OH, C 1 -C 6 alkyl or C 3 -C 8 cycloalkyl; k is 1, 2 or 3 when D is nitrogen; or is 1, 2, 3 or 4 when D is CH; m is 1 or 2; E is heteroaryl which is unsubstituted or substituted—depending upon the substitutions possible on the ring—by from one to four identical or different substituents selected from R 10 ; and R 10 is, for example, halogen, CN, NO 2 , OH, SH or C 1 -C 6 alkyl; and, where applicable, their possible E/Z isomers, E/Z isomeric mixtures and/or tautomers, in each case in free form or in salt form, a process for the preparation of those compounds and their use, pesticidal compositions in which the active ingredient has been selected from those compounds or an agrochemically acceptable salt thereof, a process for the preparation of those compositions and their use, plant propagation material treated with those compositions, and a method of controlling pests.

  该化合物的公式为：其中A0是键或C1-C6烷基桥；A1、A2和A3是C1-C6烷基桥；D是CH或N；W例如为O、S、SO、SO2、—C（═O）—O—或—O—C（═O）—；T是键或例如O、NH、S、SO或SR2；Q例如为O、S、SO或SO2；Y例如为O、S、SO或SO2；X1和X2各自独立地为氟、氯或溴；R1、R2和R3例如为H、卤素、OH、SH、CN或硝基；R4例如为H、卤素、OH、SH、CN、硝基或C1-C6烷基；R5例如为H、CN、OH、C1-C6烷基或C3-C8环烷基；当D为氮时，k为1、2或3；当D为CH时，k为1、2、3或4；m为1或2；E是杂环芳基，未取代或被从R10中选择的一个到四个相同或不同的取代基（取决于环上可能的取代物）取代；R10例如为卤素、CN、NO2、OH、SH或C1-C6烷基；以及可能的E/Z异构体、E/Z异构体混合物和/或互变异构体，在自由形式或盐形式中，制备这些化合物的方法及其用途，所述活性成分选自这些化合物或其农药学上可接受的盐的杀虫剂组合物，制备这些组合物的方法及其用途，用这些组合物处理的植物繁殖材料以及控制害虫的方法。
• OXADIAZOLE COMPOUNDS
  申请人：REMYND NV

  公开号：US20170073319A1

  公开（公告）日：2017-03-16

  The present invention relates to a compound of formula (I) or (II) or a stereoisomer, enantiomer, racemic, or tautomer thereof, (I) (II) wherein R 1 , R 2 , R 3 , L 1 , L 2 , L 3 , L 4 , L 5 and n, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of metabolic disorders and/or neurodegenerative diseases, and/or protein misfolding disorders.
• US7608631B2
  申请人：——

  公开号：US7608631B2

  公开（公告）日：2009-10-27