1-Fluorohepta-1,3,5-triyne | 591755-34-9

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代乙炔及其衍生物
• 英文名称: 1-Fluorohepta-1,3,5-triyne
• CAS: 591755-34-9
• 化学式: C₇H₃F
• 分子量: 106.1
• InChiKey: FRCVSSWHBMBCRV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• PHENANTHRENE DERIVATIVES FOR USE AS MEDICAMENTS
  申请人：VALENTIA BIOPHARMA

  公开号：US20160194274A1

  公开（公告）日：2016-07-07

  The present invention refers to phenanthrene derivatives for use as medicaments, mainly in the prevention and/or treatment of Myotonic Dystrophy Type 1, Huntington's Disease Like 2, Spinocerebellar Ataxia Type 8, Myotonic Dystrophy Type 2, Spinocerebellar Ataxia Type 3, Fragile-X-Associated Tremor/Ataxia Syndrome, Frontotemporal Degeneration/Amyotrophic Lateral Sclerosis and Spinocerebellar Ataxia Type 31. In a preferred embodiment, phenanthrene derivatives of the invention are also used as antimyotonic agents. Therefore, this invention may be included either in the whole pharmaceutical or medical field.

  本发明涉及苯并并芘衍生物作为药物的用途，主要用于预防和/或治疗肌无力型1型、亨廷顿病类2型、脊髓小脑共济失调型8型、肌无力型2型、脊髓小脑共济失调型3型、脆性X相关震颤/共济失调综合征、额颞叶退行性/肌萎缩侧索硬化和脊髓小脑共济失调型31型。在一个首选实施例中，本发明的苯并并芘衍生物也用作抗肌无力剂。因此，本发明可包括在整个制药或医学领域中。
• ISOLATION, IDENTIFICATION, AND USES OF ANTIFUNGAL COMPOUNDS
  申请人：UNIVERSITY OF UTAH RESEARCH FOUNDATION

  公开号：US20150024998A1

  公开（公告）日：2015-01-22

  In one aspect, the invention relates to isolated compounds useful as antifungal agents, for example, compounds having a structure represented by a formula: wherein R 1 is hydrogen or hydroxyl; wherein R 2 is hydrogen, a-xylose or β-xylose; and wherein R 3 and R 4 are each hydrogen or together oxygen, or a pharmaceutically acceptable salt thereof; methods of isolating and purifying same; pharmaceutical compositions comprising same; agricultural compositions comprising same; and methods of treating and/or preventing fungal infections using same. In one aspect, R 2 is not hydrogen or β-xylose when R 1 is hydroxyl and R 3 and R 4 are together oxygen. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• US7790734B2
  申请人：——

  公开号：US7790734B2

  公开（公告）日：2010-09-07