1-Ethyl-9-methoxy-3,4,6,7,12,12b-hexahydro-indolo[2,3-a]quinolizine | 140428-18-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1-Ethyl-9-methoxy-3,4,6,7,12,12b-hexahydro-indolo[2,3-a]quinolizine
• CAS: 140428-18-8
• 化学式: C₁₈H₂₂N₂O
• 分子量: 282.385
• InChiKey: QSQQUZGOGKJOQN-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  2-[2-(5-Ethyl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-5-methoxy-1H-indole 在 盐酸 、 9,10-二氰基蒽 、 三甲基氰硅烷 作用下， 生成 1-Ethyl-9-methoxy-3,4,6,7,12,12b-hexahydro-indolo[2,3-a]quinolizine
  参考文献：
  名称：

  Trimethylsilyl cyanide as a superior trapping agent for iminium ion intermediates in the dca-sensitized photooxygenation of indole derivatives and analogues. Application to the total synthesis of some indoloquinolizidine alkaloids

  摘要：

  A photoinduced electron transfer process sensitized by 9,10-dicyanoanthracene (DCA), using Me3SiCN (TMSCN) as cyanating agent, yields alpha-aminonitriles in the indole derivatives and analogues series. Efficient synthesis of indoloquinolizidine alkaloids through a Pictet-Spengler cyclization applied to these alpha-aminonitriles generated in situ is described.

  DOI：

  10.1016/s0040-4039(00)77714-8