9-(4,6-dimethyl-pyrimidin-2-yl)-4-((5-(3-isopropoxy-phenyl)-2-methyl-2H-1,2,3-triazol-4-yl)methyl)-1,4,9-triazaspiro[5.5]undecan-5-one | 1383573-67-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 9-(4,6-dimethyl-pyrimidin-2-yl)-4-((5-(3-isopropoxy-phenyl)-2-methyl-2H-1,2,3-triazol-4-yl)methyl)-1,4,9-triazaspiro[5.5]undecan-5-one
• 英文别名: 9-(4,6-Dimethylpyrimidin-2-yl)-4-[[2-methyl-5-(3-propan-2-yloxyphenyl)triazol-4-yl]methyl]-1,4,9-triazaspiro[5.5]undecan-5-one
• CAS: 1383573-67-8
• 化学式: C₂₇H₃₆N₈O₂
• 分子量: 504.635
• InChiKey: KYSCDTAUVDVABK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  37
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  101
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• [EN] DI/TRI-AZA-SPIRO-C9-C11ALKANES<br/>[FR] DI/TRI-AZA-SPIRO-(ALCANES EN C9-C11)
  申请人：NOVARTIS AG

  公开号：WO2012101487A1

  公开（公告）日：2012-08-02

  The invention relates to compounds of the formula I A-D-C(R1)2-B (I), in which A and B are aromatic ring systems and wherein D is selected from the groups D1 to D5 and the other substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.

  该发明涉及公式I A-D-C(R1)2-B（I）的化合物，其中A和B是芳香环系统，D选自D1至D5组，其他取代基如规范中定义；以自由形式或盐形式存在；其制备，用作药物以及包含它的药物。
• Di/tri-aza-spiro-C9-C11alkanes
  申请人：BADIGER Sangamesh

  公开号：US20120165331A1

  公开（公告）日：2012-06-28

  The invention relates to compounds of the formula I A-D-C(R 1 ) 2 —B  (I), in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.

  该发明涉及公式IA-D-C(R1)2—B中的化合物  (I)，其中取代基如规范中所定义；以自由形式或盐形式存在；以及其制备、用作药物和包含它的药物的用途。