Cy3.24 | 1034977-17-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: Cy3.24
• 英文别名: 6-[2-[(E)-3-[1-(5-carboxypentyl)-3,3-dimethylindol-1-ium-2-yl]prop-2-enylidene]-3,3-dimethylindol-1-yl]hexanoic acid
• CAS: 1034977-17-7
• 化学式: C₃₅H₄₅N₂O₄
• 分子量: 557.753
• InChiKey: NGNKQYJNRVVHKP-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  41
• 可旋转键数：
  14
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  80.8
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2,3,3-三甲基-3H-吲哚-5-磺酸 在 吡啶 、 邻二氯苯 作用下， 以 甲醇 为溶剂， 反应 72.0h， 生成 3-[2-[3-[1-(5-carboxypentyl)-3,3-dimethylindol-1-ium-2-yl]prop-2-enylidene]-3,3-dimethyl-5-sulfoindol-1-yl]propane-1-sulfonate 、 Cy3.24
  参考文献：
  名称：

  [EN] FUNCTIONALIZED CYANINE DYES
  [FR] COLORANTS DE TYPE CYANINE FONCTIONNALISÉS

  摘要：

  公开号：

  WO2012027618A3

文献信息

• FUNCTIONALIZED CYANINE DYES (PEG)
  申请人：Shen Gene

  公开号：US20120058482A1

  公开（公告）日：2012-03-08

  The invention provides a novel class of cyanine dyes that are functionalized with a linker moiety that facilitates their conjugation to other species and substituent groups which increase the water-solubility, and optimize the optical properties of the dyes. Also provided are conjugates of the dyes, methods of using the dyes and their conjugates and kits including the dyes and their conjugates.

  本发明提供了一种新型的靛蓝染料类，它们被功能化了连接子基团，这有助于将它们与其他物种和取代基团共价结合，从而增加了水溶性并优化了染料的光学性能。同时，还提供了染料的共价物，使用这些染料及其共价物的方法以及包括这些染料及其共价物的试剂盒。
• Cyanine dyes
  申请人：Pacific Biosciences of California, Inc.

  公开号：US10392659B2

  公开（公告）日：2019-08-27

  The invention provides a novel class of cyanine dyes that are functionalized with sulfonic acid groups and a linker moiety that facilitates their conjugation to other species and substituent groups which increase the water-solubility, and optimize the optical properties of the dyes. Also provided are conjugates of the dyes, methods of using the dyes and their conjugates and kits including the dyes and their conjugates.

  本发明提供了一类新型的氰基染料，该染料由磺酸基团和连接基团官能化，这种连接基团和取代基团可促进染料与其他物质和取代基团的共轭，从而提高染料的水溶性并优化其光学特性。此外，还提供了这些染料的共轭物、使用这些染料及其共轭物的方法以及包括这些染料及其共轭物的试剂盒。
• Cyanine Dyes
  申请人：Pacific Biosciences of California, Inc.

  公开号：US20170183501A1

  公开（公告）日：2017-06-29

  The invention provides a novel class of cyanine dyes that are functionalized with sulfonic acid groups and a linker moiety that facilitates their conjugation to other species and substituent groups which increase the water-solubility, and optimize the optical properties of the dyes. Also provided are conjugates of the dyes, methods of using the dyes and their conjugates and kits including the dyes and their conjugates.
• CYANINE DYES
  申请人：Pacific Biosciences of California, Inc.

  公开号：US20200232023A1

  公开（公告）日：2020-07-23

  The invention provides a novel class of cyanine dyes that are functionalized with sulfonic acid groups and a linker moiety that facilitates their conjugation to other species and substituent groups which increase the water-solubility, and optimize the optical properties of the dyes. Also provided are conjugates of the dyes, methods of using the dyes and their conjugates and kits including the dyes and their conjugates.
• US9920365B2
  申请人：——

  公开号：US9920365B2

  公开（公告）日：2018-03-20