6-环己基-3-(2-呋喃基)-1,2,4-三唑并[3,4-B][1,3,4]噻二唑 | 577696-37-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 中文名称: 6-环己基-3-(2-呋喃基)-1,2,4-三唑并[3,4-B][1,3,4]噻二唑
• 英文名称: 6-Cyclohexyl-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• CAS: 577696-37-8
• 化学式: C₁₃H₁₄N₄OS
• 分子量: 274.34
• InChiKey: SWTUPSNBTSPBIH-UHFFFAOYSA-N

物化性质

• 溶解度：
  DMSO：可溶，5mg/mL（澄清溶液）

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  84.5
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Methods of Producing Specialized Cardio-Like Cells from Stem Cells
  申请人：Emory University

  公开号：US20190136191A1

  公开（公告）日：2019-05-09

  This disclosure relates to method of differentiating stem cells to specific cardiac-like cells. In certain embodiments, the disclosure contemplates methods of generating left ventricular-like cells and the atrial-like cells by timing the exposure of dividing stem cells to retinoic acid (RA) or retinoic acid receptor inhibitors.
• [EN] METHODS OF PRODUCING SPECIALIZED CARDIO-LIKE CELLS FROM STEM CELL<br/>[FR] PROCÉDÉS DE PRODUCTION DE CELLULES DE TYPE CARDIAQUE SPÉCIALISÉES À PARTIR DE CELLULES SOUCHES
  申请人：UNIV EMORY

  公开号：WO2017192606A1

  公开（公告）日：2017-11-09

  This disclosure relates to method of differentiating stem cells to specific cardiac-like cells. In certain embodiments, the disclosure contemplates methods of generating left ventricular-like cells and the atrial-like cells by timing the exposure of dividing stem cells to retinoic acid (RA) or retinoic acid receptor inhibitors.