2,8-Bis(4-methoxyphenyl)pyrido[2,3-b][1,8]naphthyridine | 194716-53-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,8-Bis(4-methoxyphenyl)pyrido[2,3-b][1,8]naphthyridine
• CAS: 194716-53-5
• 化学式: C₂₅H₁₉N₃O₂
• 分子量: 393.445
• InChiKey: GAKYXKGDQIAFDE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  30
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  57.1
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2,8-Bis(4-methoxyphenyl)pyrido[2,3-b][1,8]naphthyridine 在 盐酸 、 sodium hydride 、 magnesium 、 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 水 、 N,N-二甲基甲酰胺 为溶剂， 生成 5-[4-[[3,5-Bis[(3,5-ditert-butylphenyl)methoxy]phenyl]methoxy]phenyl]-2,8-bis(4-methoxyphenyl)pyrido[2,3-b][1,8]naphthyridine
  参考文献：
  名称：

  Dendrimers with anthyridine-based hydrogen-bonding units at their cores: Synthesis, complexation and self-assembly studies

  摘要：

  Generation 1-4 Frechet-type dendritic bromides were covalently linked to anthyridine (6) to give ''sticky'' dendrons 7a-7d. The binding constants of 1:1 complexes between 7 and benzamidinium salt 8 were measured to assess their ability to act as building blocks for self-assembly. A 2:1 complex of 7 and pentamidine 9 formed in 1% CD3CN/CDCl3 indicating the utility of these compounds for constructing larger dendritic assemblies. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)01222-7
• 作为产物：
  描述：

  2,6-二氨基吡啶-3,5-二甲醛 、 对甲氧基苯乙酮 在 氢氧化钾 、 硝酸 作用下， 生成 2,8-Bis(4-methoxyphenyl)pyrido[2,3-b][1,8]naphthyridine
  参考文献：
  名称：

  Dendrimers with anthyridine-based hydrogen-bonding units at their cores: Synthesis, complexation and self-assembly studies

  摘要：

  Generation 1-4 Frechet-type dendritic bromides were covalently linked to anthyridine (6) to give ''sticky'' dendrons 7a-7d. The binding constants of 1:1 complexes between 7 and benzamidinium salt 8 were measured to assess their ability to act as building blocks for self-assembly. A 2:1 complex of 7 and pentamidine 9 formed in 1% CD3CN/CDCl3 indicating the utility of these compounds for constructing larger dendritic assemblies. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)01222-7