N-tosyl-bis(3-iodopropyl)amine | 1326626-44-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-tosyl-bis(3-iodopropyl)amine
• 英文别名: N-tosylbis(3-iodopropyl)amine
• CAS: 1326626-44-1
• 化学式: C₁₃H₁₉I₂NO₂S
• 分子量: 507.174
• InChiKey: HLJNNYDEZJGQII-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.64
• 重原子数：
  19.0
• 可旋转键数：
  8.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  37.38
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  N-tosyl-bis(3-iodopropyl)amine 在 lithium aluminium tetrahydride 、 caesium carbonate 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 102.0h， 生成 1,9-diaza-5,13-dithiocyclohexadecane
  参考文献：
  名称：

  Synthesis and characterisation of new porphyrazinato magnesium containing macrobicyclic moieties

  摘要：

  Novel porphyrazinato magnesium (MgPz) containing symmetrically four diaza-tetrathia-macrobicycles on peripheral positions was synthesized by the cyclotetramerisation reaction of 5,8,16,23-tetrathia-1,12-diazabicyclo[9.7.7]pentacosane-6-en-6,7-dicarbodinitril (9), which was prepared by sequence reaction of N-tosyl-bis[3-bis(tosyloxypropyl)] amine (1) and disodium cis-1,2-dicyano-1,2-ethylenedithiolate (8). Elemental analysis, IR, NMR, MS and UV-vis data confirmed the ability of bulky cryptand moieties to induce steric isolation of Pz core in the solid state.

  DOI：

  10.1080/10610278.2011.575468
• 作为产物：
  描述：

  bis(3-tosyloxypropyl)tosylamine 在 sodium iodide 作用下， 以 丙酮 为溶剂， 反应 3.0h， 以81.1%的产率得到N-tosyl-bis(3-iodopropyl)amine
  参考文献：
  名称：

  Synthesis and characterisation of new porphyrazinato magnesium containing macrobicyclic moieties

  摘要：

  Novel porphyrazinato magnesium (MgPz) containing symmetrically four diaza-tetrathia-macrobicycles on peripheral positions was synthesized by the cyclotetramerisation reaction of 5,8,16,23-tetrathia-1,12-diazabicyclo[9.7.7]pentacosane-6-en-6,7-dicarbodinitril (9), which was prepared by sequence reaction of N-tosyl-bis[3-bis(tosyloxypropyl)] amine (1) and disodium cis-1,2-dicyano-1,2-ethylenedithiolate (8). Elemental analysis, IR, NMR, MS and UV-vis data confirmed the ability of bulky cryptand moieties to induce steric isolation of Pz core in the solid state.

  DOI：

  10.1080/10610278.2011.575468

文献信息

• Synthesis and characterization of metal-free phthalocyanine containing 16-membered N2S2-donor macrocycles linked to a 2-pyridinyl methyl moiety
  作者：Nilgün Kabay、Yaşar Gök

  DOI：10.1016/j.tetlet.2013.05.125

  日期：2013.7

  A metal-free phthalocyanine (H2Pc) containing four diazadithiamacrocycles a with 2-pyridinyl methyl groups attached was synthesized via cyclotetramerization of 4,5-bis2-[13(2-pyridinylmethyl)-1,9-dithia-5,13-diazacyclohexadecanyl-5]ethyl} thiophthalonitrile in the presence of DBU as a strong organic base. New compounds were characterized by a combination of elemental analysis, 1H NMR, 13C NMR, IR

  通过4,5-双2- [13-（2-吡啶基甲基）-1,9-dithia-5，]的环四聚反应合成了包含四个带有2-吡啶基甲基的重氮二氮杂大环a的无金属酞菁（H 2 Pc）。在作为强有机碱的DBU存在下的13-二氮环六癸基-5]乙基}硫代邻苯二甲腈。新化合物通过元素分析，1 H NMR，13 C NMR，IR，UV / vis和MS光谱数据的组合进行表征。
• Synthesis and characterization of a new zinc phthalocyanine containing macrobicyclic moieties
  作者：Nuray Demirayak、Fatma Akkuş、Yaşar Gök

  DOI：10.1016/j.inoche.2013.09.050

  日期：2013.11

  Novel zinc phthalocyanine (ZnPc) containing symmetrically eight triaza-tetraoxa macrobicycles on peripheral positions has been synthesized in a multistep reaction sequence. The cyclotetramerization reaction was accomplished with 4,5-bis[2-(4,7,13,16-tetraoxa-1,10,22-triazabicyclo[8.8.7]pentacosane-22-yl)ethylthiolphthalonitrile (6) which was prepared by the reaction of 12-bis(2-iodoethoxy)-4,5-dicyanobenzene (5) and 4.7,13,16-tetraoxa-1,10,22-triazabicyclo[8.8.7]pentacosane (4). The novel compounds were characterized by a combination of elemental analysis, H-1 and C-13 NMR, IR, UV-vis and MS spectral data. (C) 2013 Elsevier B.V. All rights reserved.