4,4’-二甲二苯基二碲 | 56821-76-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 4,4’-二甲二苯基二碲
• 英文名称: bis(2-methoxyphenyl) ditelluride
• 英文别名: Bis(2-methoxyphenyl)ditellane；1-methoxy-2-[(2-methoxyphenyl)ditellanyl]benzene
• CAS: 56821-76-2
• 化学式: C₁₄H₁₄O₂Te₂
• 分子量: 469.464
• InChiKey: GWLQNUJKGOTBEI-UHFFFAOYSA-N

物化性质

• 熔点：
  55 °C
• 稳定性/保质期：
  遵照规定使用和储存，则不会分解。

计算性质

• 辛醇/水分配系数(LogP)：
  0.98
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 储存条件：
  存放于阴凉干燥处。

反应信息

• 作为反应物：
  描述：

  4,4’-二甲二苯基二碲 在 palladium on activated charcoal 作用下， 以 1,4-二氧六环 为溶剂， 反应 1.33h， 以75%的产率得到Bis(2-methoxyphenyl) telluride
  参考文献：
  名称：

  Thiol Peroxidase Activity of Diorganyl Tellurides

  摘要：

  A number of diorganyl tellurides, including diaryl tellurides, diheteroaryl tellurides, and alkyl aryl and dialkyl tellurides, were found to catalyze the reaction of hydrogen peroxide with thiols. The thiol peroxidase- activity of the compounds was assessed by using a H-1 NMR method previously developed in our laboratories. In this assay, thiols (N-acetylcysteine, tert-butyl mercaptan, and 1-octyl mercaptan) were oxidized in the presence of hydrogen peroxide and catalyst (0.3 mol %) and the time required to reduce the thiol concentration with 50 %, t(50), determined, In a series of 4,4'-disubstituted (R = H,Me, OH, OMe, NH2, NMe(2), NHPh, CF3) diphenyl tellurides 5, the catalytic activity increased when mesomerically electron-donating substituents were present. Attempts to correlate the catalytic efficiency, expressed as log t(50)(-1), With Hammett sigma p(+)-values were successful in the 1-octyl mercaptan (r = 0.97; n = 8) and tert-butyl mercaptan (r = 0.92; n = 8) systems. In order to study the effect of coordinating, basic, acidic, or neutral substituents on catalyst efficiency, a series of 2,2'-disubstituted (R = CH2OH, CH(2)NMe(2), COOH, COOMe, OH, OMe, NH2) diphenyl tellurides: 6 were prepared and evaluated in the three thiol systems. As compared with their 4,4'-disubstituted counterparts, the 2,2'-disubstituted compounds were generally less active. The poor catalytic activity of bis(2,6-dimethylphenyl) telluride indicates the importance of steric factors. A two-step mechanism, involving H2O2-oxidation of the diorganyl telluride to a tellurium(IV) dihydroxide and reduction by thiol with disulfide formation, is proposed to account for the observed catalysis. The similar tao values obtained in the tert-butyl mercaptan and 1-octyl mercaptan systems seem to indicate that oxidation is rate-determining in the catalytic process. This view was also corroborated by the structure/ activity results obtained with the 4,4'-disubstituted diphenyl tellurides 5, 1H NMR experiments and results obtained using spoorer oxidant (tert-butyl hydroperoxide) in the standard 1-octyl mercaptan assay.

  DOI：

  10.1021/jo00087a008
• 作为产物：
  描述：

  2-溴苯甲醚 在 magnesium 、 碲化氢 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 生成 4,4’-二甲二苯基二碲
  参考文献：
  名称：

  硒代胱氨酸和碲代胱氨酸的反应性：衍生物的结构和抗氧化活性

  摘要：

  已经制备了l-硒代胱氨酸（5）和l- tellurocystine（6），并且已经在各种pH值下进行了这些氨基酸的反应，即5和6的氧化。使用过氧化氢作为氧化剂，并在酸性和碱性介质中用过量的5和6处理过氧化氢。化合物5经氧化，得到Se IV和Se VI产物。Selenocysteic酸[HO 3 SECH 2 CH（NH 2）COOH] 9，一种新型的硒VI通过单晶X射线衍射研究对化合物进行了分离和表征。相比之下，l- tellurocystine在被H 2 O 2氧化后可得到Te II和Te IV产物。分离出两性离子有机碲酸（IV）[TeCl 3 CH 2 CH（NH 3）COOH] 13并通过NMR和IR光谱，质谱和元素分析对其进行表征。化合物13在正交晶空间群中结晶。l蛋氨酸胱氨酸，当被NaBH 4还原时产生所需的碲酸酯中间体，将其用溴乙酸捕获。此外，还合成了l和d碲半胱氨酸衍生物，[（RTeCH

  DOI：

  10.1002/chem.201803776

文献信息

• Conformational Dependence of Through-Space Tellurium-Tellurium Spin-Spin Coupling in<i>Peri</i>-Substituted Bis(Tellurides)
  作者：Fergus R. Knight、Louise M. Diamond、Kasun S. Athukorala Arachchige、Paula Sanz Camacho、Rebecca A. M. Randall、Sharon E. Ashbrook、Michael Bühl、Alexandra M. Z. Slawin、J. Derek Woollins

  DOI：10.1002/chem.201405599

  日期：2015.2.23

  C9‐C‐Te‐C(Y) dihedral angles (θ); in the solid all members adopt AB or CCt configurations, with larger Te(aryl) moieties exclusively imposing the CCt variant. Exceptionally large J(125Te,125Te) spin–spin coupling constants between 3289–3848 Hz were obtained for compounds substituted by bulky Te(aryl) groups, implying these species are locked in a CCt‐type conformation. In contrast, compounds incorporating

  带有萘，和and骨架的三个相关的周边取代的双（碲化物）系列（Nap / Acenap / Aceyl（TeY）2（Nap =萘-1,8-二基N ; Acenap = ena-5,6-二基A） ;乙炔= ac-6,6-二甲苯基Ay ; Y = Ph 1 ; Fp 2 ; Tol 3 ; An‐ p 4 ; AN- Ø 5；TP 6 ; Mes 7 ; 秘诀8）已合成，并且其固态结构通过X射线晶体学确定。分子构象被分类为两个C9-C-Te-C（Y）二面角（θ）的函数；在固体中，所有成员均采用AB或CC t构型，而较大的Te（芳基）部分则专门施加CC t变体。对于由庞大的Te（芳基）基团取代的化合物，获得了3289–3848 Hz之间的非常大的J（125 Te，125 Te）自旋-自旋偶合常数，这意味着这些物质被锁定在CC t型构象中。相反，预计掺入较小的Te（芳基）部分的化合物在溶液中会动态变
• Trifluoromethyl Derivatives of Benzooxatellurole
  作者：Ewa Pietrasiak、Amanda F. Baxter、Benson Jelier、Nico Santschi、Antonio Togni

  DOI：10.1002/hlca.201900079

  日期：2019.6

  Replacement of the iodine atom in an iodine (III) CF3‐transfer reagent with a Te‐aryl moiety was accomplished in a three‐step synthetic sequence. Three compounds of this type have been prepared, two of which were characterized by X‐ray diffraction. Single crystal structures were also obtained for three related Te(IV) compounds unreported so far (4a, 4b, 6b). Comparison with the iodine (III) analogues

  碘（III）CF 3-转移试剂中的碘原子被Te-芳基部分取代是通过三步合成顺序完成的。制备了三种这类化合物，其中两种通过X射线衍射表征。还获得了迄今未报道的三种相关的Te（IV）化合物的单晶结构（4a，4b，6b）。与碘（III）类似物的比较表明在结构上有很大的相似性，但是这些物质在热条件下显示出有趣的分解途径。除了预期的Te-CF 3键断裂以外，还观察到CF键断裂，这与碘（III）化合物不同。
• Multicomponent Reaction of Isocyanide, Ditelluride, and Mn(III) Carboxylate: Synthesis of <i>N</i>-Acyl Tellurocarbamate
  作者：Jianjian Zha、Zhuoer Wang、Bingxin Liu、Qitao Tan、Bin Xu

  DOI：10.1021/acs.orglett.2c00824

  日期：2022.4.22

  A multicomponent reaction of isocyanides, ditellurides and manganese(III) carboxylates under mild reaction conditions leads to the synthesis of various N-acyl tellurocarbamates. This method demonstrates good functional tolerance and broad substrate scope and, as a result, is especially suitable for the postfunctionalization of complicated molecules such as drugs. The given method can be further extended

  在温和的反应条件下异氰化物、二碲化物和锰 (III) 羧酸盐的多组分反应导致各种N-酰基碲氨基甲酸盐的合成。该方法表现出良好的功能耐受性和广泛的底物范围，因此特别适用于药物等复杂分子的后功能化。给定的方法可以进一步扩展到硒代氨基甲酸酯的合成。
• Highly efficient synthesis of diselenides and ditellurides catalyzed by polyoxomolybdate-based copper
  作者：Yuanyuan Deng、Xianghua Zeng、Hao Xu、Jiawei Liu、Junyong Zhang、Dongcheng Hu、Jingli Xie

  DOI：10.1039/d2nj04560e

  日期：——

  A new protocol for the polyoxomolybdate-based copper-catalyzed synthesis of diselenides and ditellurides from organic iodides and elemental selenium or tellurium with moderate to excellent yields (up to 96%) is developed. The virtue of this transformation is low catalyst loading (0.5 mol%). In addition, gram-scale experiments and the reaction mechanism are studied.

  开发了一种基于多氧钼酸盐的铜催化从有机碘化物和元素硒或碲合成二硒化物和二碲化物的新方案，产率中等至极好（高达 96%）。这种转变的优点是催化剂负载量低（0.5 mol%）。此外，还研究了克级实验和反应机理。
• Aryldiazonium salts can serve as nitrogen-based Lewis acid catalysts and their applications in the formation of photoactive charge transfer complexes
  作者：Xiaojian Ren、Qiang Liu、Zhusheng Yang、Zhixiang Wang、Xiangyu Chen

  DOI：10.1016/j.cclet.2022.107821

  日期：2023.5

  We report the Lewis acid catalysis of aryldiazonium salts, and their Lewis acidity applications in photogeneration of aryl radicals under additive-, photocatalyst- and transition metal-free conditions. In this visible light-mediated transformation, the Lewis acidic character of aryldiazonium salts enables access to the photoactive charge transfer complex with dichalcogenides. The usefulness and versatility

  我们报告了芳基重氮盐的路易斯酸催化作用，以及它们在不含添加剂、光催化剂和过渡金属的条件下在芳基光生中的路易斯酸度应用。在这种可见光介导的转化中，芳基重氮盐的路易斯酸性特性使其能够与二硫化物形成光活性电荷转移络合物。通过各种芳基重氮盐的硫属元素化，证明了这种新方案的实用性和多功能性。