1-(4-bromophenyl)-1,4-dihydro-6-ethyl-4-oxo-pyridazine-5-carboxylic acid | 134128-11-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(4-bromophenyl)-1,4-dihydro-6-ethyl-4-oxo-pyridazine-5-carboxylic acid
• 英文别名: 2-(4-Bromophenyl)-3-ethyl-5-oxopyridazine-4-carboxylic acid
• CAS: 134128-11-3
• 化学式: C₁₃H₁₁BrN₂O₃
• 分子量: 323.146
• InChiKey: IBNZXDCUJDVUDC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  70
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Substituted pyridazines, processes for making them, their use as plant growth regulators, and plant growth regulating compositions containing them
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0049971A1

  公开（公告）日：1982-04-21

  Novel substituted pyridazines are provided which exhibit plant growth regulating activity on gramineous plants such as cereals. The novel compounds are of Formula (I) wherein R' is (C1-C4) alkyl, phenyl or naphthyl each of the last two groups being optionally substituted with up to three of the same or different substituents selected from halogen, trihalomethyl, (C1-C4) alkoxy, (C1-C4) alkyl and cyano; R3 is hydrogen or a group as defined below for R5; R5 is a carboxy (-COOH) group or agronomically acceptable alkali metal salt thereof, an alkoxycarbonyl (-COOR) group or a substituted carbamoyl (-CONR'R") group, wherein R represents (C1-C4) alkyl, R' represents hydrogen or (C1-C4) alkyl and R" represents (C1-C4) alkyl; and R6 is a (C1-C4) alkyl group or an optionally substituted phenyl or naphthyl group as defined for R' above. Also provided are agronomically acceptable acid addition salts of compounds of Formula (I).

  本发明提供的新型取代哒嗪类化合物对禾本科植物（如谷物）具有植物生长调节活性。这些新型化合物如式 (I) 所示 其中，R'是(C1-C4)烷基、苯基或萘基，后两个基团中的每一个可任选被至多三个相同或不同的取代基取代，这些取代基可选自卤素、三卤甲基、(C1-C4)烷氧基、(C1-C4)烷基和氰基；R3 是氢或如下定义的 R5 基团；R5 是羧基 (-COOH) 或其农艺上可接受的碱金属盐、烷氧基羰基 (-COOR) 或取代的氨基甲酰基 (-CONR'R")，其中 R 代表 (C1-C4) 烷基，R'代表氢或 (C1-C4) 烷基，R "代表 (C1-C4) 烷基；以及 R6 是 (C1-C4) 烷基或任选取代的苯基或萘基，如上文对 R' 所定义。 还提供了农艺学上可接受的式 (I) 化合物的酸加成盐。
• A METHOD OF PREPARING PYRIDAZINONE DERIVATIVES
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0489845A1

  公开（公告）日：1992-06-17
• US4732603A
  申请人：——

  公开号：US4732603A

  公开（公告）日：1988-03-22
• US5062880A
  申请人：——

  公开号：US5062880A

  公开（公告）日：1991-11-05
• US5189163A
  申请人：——

  公开号：US5189163A

  公开（公告）日：1993-02-23