5-ethyl-oxazole-2-carboxylic acid ethyl ester | 33123-69-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5-ethyl-oxazole-2-carboxylic acid ethyl ester
• 英文别名: Ethyl 5-ethyl-1,3-oxazole-2-carboxylate
• CAS: 33123-69-2
• 化学式: C₈H₁₁NO₃
• 分子量: 169.18
• InChiKey: NFBHBPREAUIKPU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  52.3
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• INHIBITORS OF RAS-EFFECTOR PROTEIN INTERACTIONS
  申请人：Oxford University Innovation Limited

  公开号：US20210047305A1

  公开（公告）日：2021-02-18

  The present invention relates to compounds of Formula I as defined herein, and salts and solvates thereof. (I) The present invention also relates to pharmaceutical compositions comprising compounds of Formula (I), and to compounds of Formula (I) for use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which inhibition of a RAS-effector protein-protein interaction is implicated.