{4-[5-(4-dimethylaminophenyl)oxazol-2-yl]benzenesulfonylamino}-acetic acid | 511535-92-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: {4-[5-(4-dimethylaminophenyl)oxazol-2-yl]benzenesulfonylamino}-acetic acid
• 英文别名: 2-[[4-[5-[4-(Dimethylamino)phenyl]-1,3-oxazol-2-yl]phenyl]sulfonylamino]acetic acid
• CAS: 511535-92-5
• 化学式: C₁₉H₁₉N₃O₅S
• 分子量: 401.443
• InChiKey: SJEMSKLTJLMTAU-UHFFFAOYSA-N

物化性质

• 沸点：
  653.6±65.0 °C(Predicted)
• 密度：
  1.357±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  121
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes
  申请人：3-Dimensional Pharmaceuticals, Inc.

  公开号：US20030105111A1

  公开（公告）日：2003-06-05

  The present invention is directed to a compound of Formula I: 1 wherein A, R 1 , and R 2 are defined herein. The present invention is also directed to compositions comprising compounds of Formula I, methods of using compounds of Formula I, and methods of making compounds of Formula I.

  本发明涉及一种具有以下结构的化合物：其中A、R1和R2在此处被定义。本发明还涉及包含Formula I化合物的组合物、使用Formula I化合物的方法以及制备Formula I化合物的方法。
• SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES
  申请人：3-DIMENSIONAL PHARMACEUTICALS, INC.

  公开号：EP1442027A1

  公开（公告）日：2004-08-04
• US6815445B2
  申请人：——

  公开号：US6815445B2

  公开（公告）日：2004-11-09
• US7078406B2
  申请人：——

  公开号：US7078406B2

  公开（公告）日：2006-07-18
• [EN] SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES<br/>[FR] DIPHENYLOXAZOLES SUBSTITUES ; SYNTHESE ET UTILISATION COMME SONDES A FLUORESCENCE
  申请人：DIMENSIONAL PHARM INC

  公开号：WO2003031419A1

  公开（公告）日：2003-04-17

  The present invention is directed to a compound of Formula (I); wherein A, R?1, and R2¿ are defined herein. The present invention is also directed to compositions comprising compounds of Formula (I), methods of using compounds of Formula (I), and methods of making compounds of Formula (I).