cyclohexyl 2,3-dideoxy-4,6-di-O-methyl-α-D-erythro-hex-2-enopyranoside | 243125-07-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃
• 英文名称: cyclohexyl 2,3-dideoxy-4,6-di-O-methyl-α-D-erythro-hex-2-enopyranoside
• CAS: 243125-07-7
• 化学式: C₁₄H₂₄O₄
• 分子量: 256.342
• InChiKey: FPXNGNCHSNYVEO-MJBXVCDLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.28
• 重原子数：
  18.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  36.92
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  cyclohexyl 2,3-dideoxy-4,6-di-O-methyl-α-D-erythro-hex-2-enopyranoside 在 palladium on activated charcoal 氢气 作用下， 以 乙酸乙酯 为溶剂， 反应 8.0h， 以65%的产率得到cyclohexyl 2,3-dideoxy-4,6-di-O-methyl-α-D-erythro-hexopyranoside
  参考文献：
  名称：

  Synthesis of 2,3-UNSATURATED 4-Amino Sugars and Cyclohexyl 2,3-Di-O-Acetyl-4,6-Di-O-Methyl-α-D-Manno-Pyranoside from Cyclohexyl 4,6-Di-O-Acetyl-2,3-Dideoxy-α-D-erythro-Hex-2-Enopyranoside

  摘要：

  The synthesis of three 2,3-unsaturated 4-amino sugars 2-4 and cyclohexyl 2,3-di-O-acetyl-4,6-di-O-methyl-alpha-D-mannopyranoside 8 starting from cyclohexyl 4,6-di-O-acetyl-2,3-dideoxy-alpha-D-erythro-hex-2-enopyranoside 1 is described. The amino sugars were prepared by allylic substitution using a palladium catalyst.

  DOI：

  10.1080/07328309908544023
• 作为产物：
  描述：

  cyclohexyl 2,3-dideoxy-α-D-erythro-hex-2-enopyranoside 、 碘甲烷 在 sodium hydride 作用下， 以 乙二醇二甲醚 为溶剂， 反应 3.0h， 以81.5%的产率得到cyclohexyl 2,3-dideoxy-4,6-di-O-methyl-α-D-erythro-hex-2-enopyranoside
  参考文献：
  名称：

  Synthesis of 2,3-UNSATURATED 4-Amino Sugars and Cyclohexyl 2,3-Di-O-Acetyl-4,6-Di-O-Methyl-α-D-Manno-Pyranoside from Cyclohexyl 4,6-Di-O-Acetyl-2,3-Dideoxy-α-D-erythro-Hex-2-Enopyranoside

  摘要：

  The synthesis of three 2,3-unsaturated 4-amino sugars 2-4 and cyclohexyl 2,3-di-O-acetyl-4,6-di-O-methyl-alpha-D-mannopyranoside 8 starting from cyclohexyl 4,6-di-O-acetyl-2,3-dideoxy-alpha-D-erythro-hex-2-enopyranoside 1 is described. The amino sugars were prepared by allylic substitution using a palladium catalyst.

  DOI：

  10.1080/07328309908544023