(5Z,8Z,11Z,13E)-(R)-15-Hydroperoxy-icosa-5,8,11,13-tetraeneperoxoic acid | 139527-49-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (5Z,8Z,11Z,13E)-(R)-15-Hydroperoxy-icosa-5,8,11,13-tetraeneperoxoic acid
• CAS: 139527-49-4
• 化学式: C₂₀H₃₂O₅
• 分子量: 352.471
• InChiKey: FNVMNHPEECQPIU-UDQWCNDOSA-N

反应信息

• 作为反应物：
  描述：

  (5Z,8Z,11Z,13E)-(R)-15-Hydroperoxy-icosa-5,8,11,13-tetraeneperoxoic acid 在 环庚烯 作用下， 生成 (5Z,8Z,11Z,13E)-(R)-15-Hydroperoxy-icosa-5,8,11,13-tetraenoic acid
  参考文献：
  名称：

  The total synthesis of 15(S)-HPETE (hydroperoxyeicosatetraenoic acid)

  摘要：

  The total synthesis of 15(S)-HPETE in enantiomerically pure form is achieved through C=C bond formation in the presence of a masked hydroperoxide. Selective reduction of a peracid in the presence of a hydroperoxide affords a mild method for removal of an HPETE methyl ester.

  DOI：

  10.1021/jo00033a006
• 作为产物：
  描述：

  (5Z,8Z,11Z,13E)-(R)-15-Hydroperoxy-icosa-5,8,11,13-tetraenoic acid methyl ester 在 lithium hydroxide 、 双氧水 作用下， 以 四氢呋喃 、 水 为溶剂， 生成 (5Z,8Z,11Z,13E)-(R)-15-Hydroperoxy-icosa-5,8,11,13-tetraeneperoxoic acid
  参考文献：
  名称：

  The total synthesis of 15(S)-HPETE (hydroperoxyeicosatetraenoic acid)

  摘要：

  The total synthesis of 15(S)-HPETE in enantiomerically pure form is achieved through C=C bond formation in the presence of a masked hydroperoxide. Selective reduction of a peracid in the presence of a hydroperoxide affords a mild method for removal of an HPETE methyl ester.

  DOI：

  10.1021/jo00033a006