(E)-6-butyl-7-carboethoxy-1-heptenylzinc iodide | 153742-74-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-6-butyl-7-carboethoxy-1-heptenylzinc iodide
• CAS: 153742-74-6
• 化学式: C₁₄H₂₅IO₂Zn
• 分子量: 417.646
• InChiKey: HHMWQGWGXFIJJT-UHFFFAOYSA-M

反应信息

• 作为产物：
  描述：

  ethyl (E)-3-butyl-8-iodo-7-octenoate 、 zinc(II) iodide 在 正丁基锂 作用下， 以 四氢呋喃 、 乙醚 、 正戊烷 为溶剂， 以80%的产率得到(E)-6-butyl-7-carboethoxy-1-heptenylzinc iodide
  参考文献：
  名称：

  Preparation of polyfunctional olefins and allenes using 1,1-bimetallics of zinc and zirconium

  摘要：

  The hydrozirconation of various alkenylzinc halides with Cp2Zr(H)Cl in dry dichloromethane provides 1,1-dimetalloalkanes of zinc and zirconium which react with aldehydes, providing (E)-alkenes with good to excellent stereoselectivity (up to 98% E). The reaction tolerates the presence of a wide range of functionalities in the dimetallic species as well as in the aldehyde, allowing the preparation of functionalized olefins. Ketones can also be olefinated by these reagents. However, only a moderate stereoselectivity is observed. The hydrozirconation of alkynylzinc halides with CP2Zr(H)Cl gives 1,1-dimetalloalkenes of zinc and zirconium which react with aldehydes, affording allenes. The olefination of alpha,beta-unsaturated aldehydes provides a short access of 1,2,4-trienes.

  DOI：

  10.1021/om00013a020