5-(1H-Imidazol-1-yl)-2-methoxybenzaldehyde | 385802-43-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5-(1H-Imidazol-1-yl)-2-methoxybenzaldehyde
• 英文别名: 5-Imidazol-1-yl-2-methoxybenzaldehyde
• CAS: 385802-43-7
• 化学式: C₁₁H₁₀N₂O₂
• 分子量: 202.213
• InChiKey: BQXYKJUZDRSWIE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  44.1
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Benzhydryl derivatives
  申请人：——

  公开号：US20030176430A1

  公开（公告）日：2003-09-18

  A compound of the formula (I): in which Z, R 1 , R 2 , R 8 , R 10 , R 11 , R 12 , R 13 and R 14 are each as defined in the description, or a salt thereof. The object compound of the present invention has pharmacological activities such as Tachykinin antagonism, and is useful for manufacture of a medicament for treating or preventing Tachykinin-mediated diseases.

  公式（I）的化合物：其中Z、R1、R2、R8、R10、R11、R12、R13和R14如描述中所定义，或其盐。本发明的目标化合物具有如Tachykinin拮抗等药理活性，并可用于制备用于治疗或预防Tachykinin介导疾病的药物。
• BENZHYDRYL DERIVATIVES
  申请人：FUJISAWA PHARMACEUTICAL CO., LTD.

  公开号：EP1294700A2

  公开（公告）日：2003-03-26
• US6787543B2
  申请人：——

  公开号：US6787543B2

  公开（公告）日：2004-09-07
• [EN] BENZHYDRYL DERIVATIVES<br/>[FR] DERIVES DE BENZHYDRYLE
  申请人：FUJISAWA PHARMACEUTICAL CO

  公开号：WO2002000631A2

  公开（公告）日：2002-01-03

  A compound of the formula (I): in which Z, R?1, R2, R8, R10, R11, R12, R13 and R14¿ are each as defined in the description, or a salt thereof. The object compound of the present invention has pharmacological activities such as Tachykinin antagonism, and is useful for manufacture of a medicament for treating or preventing Tachykinin-mediated diseases.