4,7,10-十六碳三烯酸 | 10404-91-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 4,7,10-十六碳三烯酸
• 英文名称: (4E,7E,10E)-hexadecatrienoic acid
• 英文别名: 4,7,10- hexadecatrienoic acid；4,7,10-Hexadecatrienoic acid；(4E,7E,10E)-hexadeca-4,7,10-trienoic acid
• CAS: 10404-91-8
• 化学式: C₁₆H₂₆O₂
• 分子量: 250.381
• InChiKey: SBIXFICRPNNLIR-YHTMAJSVSA-N

物化性质

• 沸点：
  351.7±21.0 °C(Predicted)
• 密度：
  0.933±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  18
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2916190090

反应信息

• 作为产物：
  描述：

  3-(4E,7E,10E-hexadeca-4,7,10-trienoyloxy)-2-hydroxypropyl icosanoate 在 potassium hydroxide 、 盐酸 作用下， 以 乙醇 、 苯 、 水 为溶剂， 反应 24.0h， 生成 二十酸 、 4,7,10-十六碳三烯酸
  参考文献：
  名称：

  Anti-H5N1 virus new diglyceride ester from the Red Sea grassThallasodendron ciliatum

  摘要：

  Some Egyptian plants were screened against highly pathogenic avian influenza strain H5N1 using plaque inhibition assay in Madin-Darby canine kidney. The results indicated that the extracts of Red Sea grass Thallasodendron ciliatum possessed potent antiviral activity (100% inhibition at the concentration of 1gmL(-1)). The bioactivity-guided fractionations led to the isolation of a new diglyceride ester (1) along with asebotin (2) for the first time from the plant. The two isolates showed reduction of virus titre by 67.26% and 53.81% inhibition at concentration of 1ngmL(-1), respectively.

  DOI：

  10.1080/14786419.2012.742082

文献信息

• PHARMACEUTICAL COMPOSITION AND METHODS
  申请人：Lipocine Inc.

  公开号：EP3185873A1

  公开（公告）日：2017-07-05
• (17-ß)-3-OXOANDROST-4-EN-17-YL UNDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
  申请人：Lipocine Inc.

  公开号：US20160193225A1

  公开（公告）日：2016-07-07

  Disclosed herein are compositions having a lipophilic active agent and methods of their use.
• (17-ß)-3-Oxoandrost-4-En-17-Yl Undecanoate Compositions and Methods of Their Preparation and Use
  申请人：Lipocine Inc.

  公开号：US20180104257A1

  公开（公告）日：2018-04-19

  Disclosed herein are compositions having a lipophilic active agent and methods of their use.
• MACROCYCLIC MUSK LACTONES AND USES THEREOF
  申请人：Blue California

  公开号：US20220298451A1

  公开（公告）日：2022-09-22

  Provided herein are uses of lactones, such as macrocyclic lactones, for use in consumer products.
• [EN] (17-β)-3-OXOANDROST-4-EN-17-YL UNDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE<br/>[FR] COMPOSITIONS D'UNDÉCANOATE DE (17-Β)-3-OXO-ANDROST-4-ÉN -17-YLE, ET PROCÉDÉS DE PRÉPARATION ET D'UTILISATION DE CEUX-CI
  申请人：LIPOCINE INC

  公开号：WO2016033611A1

  公开（公告）日：2016-03-03

  Disclosed herein are compositions having a lipophilic active agent and methods of their use. This invention further discloses substantially pure (17-beta)-3-0xoandrost-4-en-17-yl undecanoate includes (17-beta)-3-0xoandrost-4-en-17-yl undecanoate substantially free of synthetic impurities, decomposition impurities or both.