4,7,10-十六碳三烯酸甲酯 | 17364-31-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 4,7,10-十六碳三烯酸甲酯
• 英文名称: 4, 7, 10-Hexadecatrienoic acid, methyl ester
• 英文别名: Methyl (4E,7E,10E)-Hexadeca-4,7,10-Trienoate；Methyl 4,7,10-hexadecatrienoate
• CAS: 17364-31-7
• 化学式: C₁₇H₂₈O₂
• 分子量: 264.408
• InChiKey: QXIXLIQMMRFWPB-SPOHZTNBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  19
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  甲醇 、 3-(4E,7E,10E-hexadeca-4,7,10-trienoyloxy)-2-hydroxypropyl icosanoate 生成 花生酸甲酯 、 4,7,10-十六碳三烯酸甲酯
  参考文献：
  名称：

  Anti-H5N1 virus new diglyceride ester from the Red Sea grassThallasodendron ciliatum

  摘要：

  Some Egyptian plants were screened against highly pathogenic avian influenza strain H5N1 using plaque inhibition assay in Madin-Darby canine kidney. The results indicated that the extracts of Red Sea grass Thallasodendron ciliatum possessed potent antiviral activity (100% inhibition at the concentration of 1gmL(-1)). The bioactivity-guided fractionations led to the isolation of a new diglyceride ester (1) along with asebotin (2) for the first time from the plant. The two isolates showed reduction of virus titre by 67.26% and 53.81% inhibition at concentration of 1ngmL(-1), respectively.

  DOI：

  10.1080/14786419.2012.742082

文献信息

• Anti-H5N1 virus new diglyceride ester from the Red Sea grass<i>Thallasodendron ciliatum</i>
  作者：Amany K. Ibrahim、Ahmed I. Youssef、Abdel Satar Arafa、Reda Foad、Mohamed M. Radwan、Samir Ross、Hashim A. Hassanean、Safwat A. Ahmed

  DOI：10.1080/14786419.2012.742082

  日期：2013.9

  Some Egyptian plants were screened against highly pathogenic avian influenza strain H5N1 using plaque inhibition assay in Madin-Darby canine kidney. The results indicated that the extracts of Red Sea grass Thallasodendron ciliatum possessed potent antiviral activity (100% inhibition at the concentration of 1gmL(-1)). The bioactivity-guided fractionations led to the isolation of a new diglyceride ester (1) along with asebotin (2) for the first time from the plant. The two isolates showed reduction of virus titre by 67.26% and 53.81% inhibition at concentration of 1ngmL(-1), respectively.