| 913069-69-9

• 分子结构分类: 有机化合物 - 有机杂环化合物
• CAS: 913069-69-9
• 化学式: C₆₅H₁₁₂O₁₃SSi₃
• 分子量: 1217.92
• InChiKey: WDFOKCJOZGOZLB-HSTPNUBISA-N

反应信息

• 作为反应物：
  描述：

  在 偶氮二异丁腈 、 三苯基氢化锡 作用下， 以 甲苯 为溶剂， 以77%的产率得到
  参考文献：
  名称：

  Structure–activity relationship studies of gymnocin-A

  摘要：

  The structural elements required for cytotoxicity of gymnocin-A, a polycyclic ether isolated from the red tide-forming dinoflagellate, Karenia mikimotoi, were investigated by the total synthesis and evaluation of the structural analogues. The results of the structure-activity relationship studies indicated that the alpha,beta-unsaturated aldehyde functionality of the side chain as well as the molecular length were needed for exhibiting the cytotoxicity of gymnocin-A. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.07.081
• 作为产物：
  描述：

  、 叔丁基二甲硅基三氟甲磺酸酯 在 2,6-二甲基吡啶 作用下， 以 二氯甲烷 为溶剂， 以84%的产率得到
  参考文献：
  名称：

  Structure–activity relationship studies of gymnocin-A

  摘要：

  The structural elements required for cytotoxicity of gymnocin-A, a polycyclic ether isolated from the red tide-forming dinoflagellate, Karenia mikimotoi, were investigated by the total synthesis and evaluation of the structural analogues. The results of the structure-activity relationship studies indicated that the alpha,beta-unsaturated aldehyde functionality of the side chain as well as the molecular length were needed for exhibiting the cytotoxicity of gymnocin-A. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.07.081