4,5-diamino-1-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one | 859296-69-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4,5-diamino-1-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one
• 英文别名: 4,5-Diamino-1-methyl-2-phenyl-1,2-dihydro-pyrazol-3-on；4,5-diamino-2-phenyl-1-methyl-1,2-dihydropyrazol-3-one；4,5-Diamino-1-methyl-2-phenylpyrazol-3-one
• CAS: 859296-69-8
• 化学式: C₁₀H₁₂N₄O
• 分子量: 204.231
• InChiKey: MWPGNMDZNJOMNI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  75.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4,5-diamino-1-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one 在 盐酸 、 sodium nitrite 作用下， 生成 4-methyl-5-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d][1,2,3]triazol-6-one
  参考文献：
  名称：

  关于3-氨基吡唑啉酮的知识-（5）

  摘要：

  制备了1-苯基-2-甲基-3-氨基-5-吡唑啉酮（3-氨基-比林酮）与1-苯基-2,3-二甲基-5-吡唑酮的异构体的代表，并与它们的同分异构体一起使用。发现了相应的1-苯基-2-甲基-3-亚氨基-5-吡唑啉酮。介观比取决于4-位的取代类型。根据霍夫曼或库尔蒂乌斯的羧酸降解在某些情况下会导致亚氨基化合物，其次导致含氧化合物。

  DOI：

  10.1002/hlca.19500330509
• 作为产物：
  描述：

  5-Amino-1,2-dihydro-1-methyl-2-phenylpyrazol-3-one 在 盐酸 、 乙醇 、 水 、 镍 、 sodium nitrite 作用下， 生成 4,5-diamino-1-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one
  参考文献：
  名称：

  关于3-氨基吡唑啉酮的知识-（5）

  摘要：

  制备了1-苯基-2-甲基-3-氨基-5-吡唑啉酮（3-氨基-比林酮）与1-苯基-2,3-二甲基-5-吡唑酮的异构体的代表，并与它们的同分异构体一起使用。发现了相应的1-苯基-2-甲基-3-亚氨基-5-吡唑啉酮。介观比取决于4-位的取代类型。根据霍夫曼或库尔蒂乌斯的羧酸降解在某些情况下会导致亚氨基化合物，其次导致含氧化合物。

  DOI：

  10.1002/hlca.19500330509

文献信息

• Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler and at least one associative polyurethane polymer
  申请人：Saunier Jean-Baptiste

  公开号：US20060277693A1

  公开（公告）日：2006-12-14

  The present disclosure relates to a composition for dyeing keratin fibers, for example, human keratin fibers such as the hair, comprising at least one oxidation base chosen from diamino-N,N-dihydropyrazolone compounds and addition salts thereof, at least one coupler and at least one associative polyurethane polymer, and also to a dyeing process and kit using such a composition. The present disclosure makes it possible, for instance, to obtain fast coloration of keratin fibers that is resistant to light and to washing.

  本公开涉及一种用于染色角蛋白纤维的组合物，例如人类角蛋白纤维，如头发，包括至少选择自二氨基-N，N-二氢吡唑酮化合物及其盐的氧化碱、至少一种偶联剂和至少一种缔合型聚氨酯聚合物，以及使用这种组合物的染色过程和套件。本公开使得例如可以获得对光线和水洗具有抗性的角蛋白纤维的快速着色。
• Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler, and at least one surfactant
  申请人：Saunier Jean-Baptiste

  公开号：US20060277692A1

  公开（公告）日：2006-12-14

  Disclosed herein is a composition for dyeing keratin fibers, for example, human keratin fibers such as the hair, comprising at least one oxidation base chosen from diamino-N,N-dihydropyrazolones and the addition salts thereof, at least one coupler, and at least one surfactant chosen from (C 8 -C 30 )alkyl ether carboxylic acids and salts thereof, (C 12 -C 30 )alkyl polyglucosides, monoglycerolated surfactants, and polyglycerolated surfactants. Also disclosed herein is a method for dyeing keratin fibers comprising applying a composition in accordance with the present disclosure to the keratin fibers. The compositions and methods of the present disclosure may makes it possible to obtain fast coloration of keratin fibers that is resistant to light and/or to washing.

  本文揭示了一种用于染色角蛋白纤维的配方，例如人类角蛋白纤维，如头发，包括至少选择自二氨基-N，N-二氢吡唑酮和其盐的氧化碱，至少一种偶联剂，以及至少选择自（C8-C30）烷基醚羧酸及其盐，（C12-C30）烷基聚葡糖苷，单甘油酯表面活性剂和聚甘油酯表面活性剂的表面活性剂。本文还揭示了一种染色角蛋白纤维的方法，包括将根据本公开的配方应用于角蛋白纤维。本公开的配方和方法可以实现对角蛋白纤维进行快速染色，且具有抗光和/或洗涤的特性。
• Composition for dyeing keratin fibers, comprising a diamino-N,N-dihydropyrazolone compound, a coupler, and a polyol
  申请人：Saunier Jean-Baptiste

  公开号：US20060277691A1

  公开（公告）日：2006-12-14

  The present disclosure relates to a composition for dyeing keratin fibers, for instance human keratin fibers such as the hair, comprising at least one oxidation base chosen from diamino-N,N-dihydropyrazolone compounds and addition salts thereof, at least one coupler and at least one C 4 -C 30 polyol. The present disclosure also relates to the dyeing process and kit using the composition as presently disclosed. Use of the present disclosure makes it, for example, possible to obtain fast coloration of keratin fibers that is resistant to light and to washing.

  本公开涉及一种用于染色角蛋白纤维的组合物，例如人类角蛋白纤维，如头发，包括至少选择自二氨基-N，N-二氢吡唑酮化合物及其盐的氧化碱、至少一种偶联剂和至少一种C4-C30多元醇。本公开还涉及使用所述组合物的染色过程和套件。例如，使用本公开可以实现对角蛋白纤维的快速着色，且具有抗光和抗洗的特性。
• Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler, and at least one heterocyclic direct dye
  申请人：Hercouet Leila

  公开号：US20070006398A1

  公开（公告）日：2007-01-11

  Disclose herein is a composition for dyeing keratin fibers, for example, human keratin fibers such as the hair, comprising at least one oxidation base chosen from diamino-N,N-dihydropyrazolones and addition salts thereof, at least one coupler, and at least one heterocyclic direct dye. Also disclosed herein is a method for dyeing keratin fibers comprising applying a composition of the present disclosure to the keratin fibers. The compositions and methods of the present disclosure may make it possible to obtain fast coloration of keratin fibers that is resistant to light and/or to washing.

  本文披露了一种用于染色角蛋白纤维的组合物，例如，人类角蛋白纤维如头发，包括至少选择自二氨基-N，N-二氢吡唑酮和其盐中的至少一种氧化碱，至少一种偶联剂，以及至少一种杂环直接染料。本文还披露了一种染色角蛋白纤维的方法，包括将本文所述的组合物应用于角蛋白纤维。本文所披露的组合物和方法可能使得能够获得对光线和/或洗涤具有抗性的角蛋白纤维的快速着色。
• COMPOSITION FOR OXIDATION DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE OXIDATION BASE, AT LEAST ONE DYE PRECURSOR, AT LEAST ONE OXIDIZING AGENT, AND OPTIONALLY AT LEAST ONE ALKALINE AGENT, AND PROCESSES AND KITS THEREWITH
  申请人：AUDOUSSET Marie-Pascale

  公开号：US20100162493A1

  公开（公告）日：2010-07-01

  The disclosure relates to a composition for the oxidation dyeing of keratin fibers comprising: A) at least one fatty substance wherein the at least one fatty substance is present in an amount greater than or equal to 25% by weight relative to the total weight of the composition; B) at least one oxidation base chosen from diaminopyrazolones and acid-addition salts thereof; C) at least one additional dye precursor other than the oxidation base in B); D) at least one oxidizing agent; and optionally E) at least one alkaline agent.

  本发明涉及一种用于氧化染色角蛋白纤维的组合物，其中包括：A）至少一种脂肪物质，其中所述至少一种脂肪物质相对于组合物的总重量存在量大于或等于25％；B）至少一种氧化碱，所述氧化碱选择自二氨基吡唑烷酮及其酸加成盐；C）至少一种除B）中的氧化碱以外的额外染料前体；D）至少一种氧化剂；和可选的E）至少一种碱性剂。