Glu[Glu(OMe)-OMe]Glu(OMe)-OMe | 188636-65-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Glu[Glu(OMe)-OMe]Glu(OMe)-OMe
• CAS: 188636-65-9
• 化学式: C₁₉H₃₁N₃O₁₀
• 分子量: 461.469
• InChiKey: NCTSYZAKGAIRMY-AVGNSLFASA-N

物化性质

• 沸点：
  655.6±55.0 °C(Predicted)
• 密度：
  1.237±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.68
• 重原子数：
  32.0
• 可旋转键数：
  14.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  189.42
• 氢给体数：
  3.0
• 氢受体数：
  11.0

反应信息

• 作为反应物：
  描述：

  Glu[Glu(OMe)-OMe]Glu(OMe)-OMe 在 copper(l) iodide 、 三乙胺 、 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 、 乙腈 为溶剂， 反应 29.5h， 生成
  参考文献：
  名称：

  Peptide dendrimers with designer core for directed self-assembly

  摘要：

  A series of designer peptide dendrimers with urea and urea-triazole cores were synthesized. Urea cored dendrimers assembled into fibrillar morphology, while dendrimers with urea-triazole core assembled into vesicular morphology. The core-dependent self-assembly behavior is studied by ultramicroscopy, Xray crystallography and supported by molecular dynamics simulation. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2015.09.043
• 作为产物：
  描述：

  L-谷氨酸二甲酯盐酸盐 在 N-羟基丁二酰亚胺 、 palladium 10% on activated carbon 、 氢气 、 三乙胺 、 N,N'-二环己基碳二亚胺 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 25.5h， 生成 Glu[Glu(OMe)-OMe]Glu(OMe)-OMe
  参考文献：
  名称：

  Peptide dendrimers with designer core for directed self-assembly

  摘要：

  A series of designer peptide dendrimers with urea and urea-triazole cores were synthesized. Urea cored dendrimers assembled into fibrillar morphology, while dendrimers with urea-triazole core assembled into vesicular morphology. The core-dependent self-assembly behavior is studied by ultramicroscopy, Xray crystallography and supported by molecular dynamics simulation. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2015.09.043

文献信息

• Synthesis and Properties of DNA Complexes Containing 2,2,6,6-Tetramethyl-1-piperidinoxy (TEMPO) Moieties as Organic Radical Battery Materials
  作者：Jinqing Qu、Ryuhei Morita、Masaharu Satoh、Jun Wada、Fumiaki Terakura、Kenji Mizoguchi、Naoya Ogata、Toshio Masuda

  DOI：10.1002/chem.200800021

  日期：2008.4.7

  report here the first example of organic radical battery with DNA. Though there is a growing interest in DNA/cationic-lipid complexes as promising gene delivery vehicles, few efforts have been focused on the use of such complexes as advanced materials for organic optoelectronic applications. The present article describes how substitution of the sodium counter cation of DNA with cationic amphiphilic lipid(1-4)

  我们在这里报告带有DNA的有机自由基电池的第一个例子。尽管对DNA /阳离子-脂质复合物作为有前途的基因递送载体的兴趣日益增长，但很少有努力集中在将这种复合物用作有机光电应用的先进材料。本文介绍了如何用阳离子两亲性脂质（1-4）取代DNA的钠抗衡阳离子，从而提供含有TEMPO自由基的新型DNA-脂质复合物，其中磷酸盐与脂质的实际摩尔比为1：0.84至1： 0.16。所有含TEMPO的DNA-脂质复合物均显示出可逆的两阶段充电/放电过程，其放电容量为40.5-60.0 A h kg（-1）。特别是，基于DNA-脂质（3）的细胞的容量达到60.0 A h kg（-1），
• Synthesis of totally chiral, multiple armed, poly Glu and poly Asp scaffoldings on bifunctional adamantane core
  作者：Darshan Ranganathan、Sunita Kurur

  DOI：10.1016/s0040-4039(97)00054-3

  日期：1997.2

  Three successive generations of peptidic scaffoldings consisting of two, six and fourteen chiral (all L) centres and four, eight and sixteen carbomethoxy groups, respectively, at the periphery with adamantane nucleus as the central core have been constructed by linking the two halves of corresponding Asp/Glu dendrons by 1,3-bifunctional adamantane unit. Energy minimization and H-1 NMR studies have shown these scaffoldings to adopt increasingly globular and compact architecture with each succeeding generation. (C) 1997, Published by Elsevier Science Ltd.