(3S,5R)-5,9-dimethyl-3,5-dihydroxy-8-decen-1-ol | 179949-39-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (3S,5R)-5,9-dimethyl-3,5-dihydroxy-8-decen-1-ol
• CAS: 179949-39-4
• 化学式: C₁₂H₂₄O₃
• 分子量: 216.321
• InChiKey: CCDIXMHQZUKQIV-NWDGAFQWSA-N

反应信息

• 作为反应物：
  描述：

  (3S,5R)-5,9-dimethyl-3,5-dihydroxy-8-decen-1-ol 在 咪唑 、 camphorsulfonique acid 作用下， 反应 14.75h， 生成 tert-Butyl-diphenyl-{2-[(4S,6R)-2,2,6-trimethyl-6-(4-methyl-pent-3-enyl)-[1,3]dioxan-4-yl]-ethoxy}-silane
  参考文献：
  名称：

  Enhanced diastereoselectivity in the addition of ester enolate to optically active α,β-epoxyaldehydes obtained from nerol and geraniol

  摘要：

  Optically active alpha,beta-epoxyaldehydes obtained from nerol and geraniol were allowed to react with lithium tert-butylacetate. The diastereofacial preference of the aldolisation reaction was always anti (''Si''face attack of the carbonyl). The best diastereoselectivity ever observed in these series (>99 : <1 anti : syn) was obtained for the alpha,beta-epoxyneral aldolisation. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0040-4020(96)00453-x
• 作为产物：
  描述：

  在 红铝 作用下， 以 四氢呋喃 为溶剂， 反应 13.0h， 以77%的产率得到(3S,5R)-5,9-dimethyl-3,5-dihydroxy-8-decen-1-ol
  参考文献：
  名称：

  Enhanced diastereoselectivity in the addition of ester enolate to optically active α,β-epoxyaldehydes obtained from nerol and geraniol

  摘要：

  Optically active alpha,beta-epoxyaldehydes obtained from nerol and geraniol were allowed to react with lithium tert-butylacetate. The diastereofacial preference of the aldolisation reaction was always anti (''Si''face attack of the carbonyl). The best diastereoselectivity ever observed in these series (>99 : <1 anti : syn) was obtained for the alpha,beta-epoxyneral aldolisation. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0040-4020(96)00453-x