3-T-Butyl-1-(2-hydroxyethyl)pyrazole | 1255574-70-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3-T-Butyl-1-(2-hydroxyethyl)pyrazole
• 英文别名: 2-(3-tert-butylpyrazol-1-yl)ethanol
• CAS: 1255574-70-9
• 化学式: C₉H₁₆N₂O
• 分子量: 168.24
• InChiKey: IBOFWWFXTWVQTR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  38
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Biaryl inhibitors of Bruton'S tyrosine kinase
  申请人：BIOGEN MA INC.

  公开号：US10759783B2

  公开（公告）日：2020-09-01

  The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

  本发明提供了可用作布鲁顿酪氨酸激酶抑制剂并表现出理想特性的化合物及其组合物。
• BIARYL INHIBITORS OF BRUTON'S TYROSINE KINASE
  申请人：BIOGEN MA INC.

  公开号：US20180093973A1

  公开（公告）日：2018-04-05

  The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
• SSAO INHIBITORS AND USES THEREOF
  申请人：METACRINE, INC.

  公开号：US20200181104A1

  公开（公告）日：2020-06-11

  Described herein are compounds that are semicarbazide-sensitive amine oxidase (SSAO) inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in treating or preventing a liver disease or condition.
• US9809577B2
  申请人：——

  公开号：US9809577B2

  公开（公告）日：2017-11-07