(1R,3aS,7aR)-1,3,3a,4,7,7a-hexahydro-2-benzofuran-1-ol | 1002723-41-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异苯并呋喃
• 英文名称: (1R,3aS,7aR)-1,3,3a,4,7,7a-hexahydro-2-benzofuran-1-ol
• CAS: 1002723-41-2
• 化学式: C₈H₁₂O₂
• 分子量: 140.182
• InChiKey: NZSCXAOKLDNKQZ-BWZBUEFSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  cis-8-oxabicyclo<4.3.0>non-3-ene 在 chiral binaphthyl Mn(salen) complex, Ar = 3,5-F₂C₆H₃ 亚碘酰苯 作用下， 以 氯苯 为溶剂， 反应 36.0h， 生成 (1S,3aR,7aS)-1,3,3a,4,7,7a-hexahydro-2-benzofuran-1-ol 、 (1R,3aS,7aR)-1,3,3a,4,7,7a-hexahydro-2-benzofuran-1-ol
  参考文献：
  名称：

  Oxidative desymmetrization of meso-cyclic ethers (2): Recognition of the core structure of substrates of the Mn(salen) catalyst

  摘要：

  Mn(salen) complexes bearing a binaphthyl chiral unit serve as catalysts for oxidative desymmetrization of meso-cyclic ethers. This study revealed that chiral recognition by the complex is strongly influenced by the core structure of substrates and this recognition is adjusted by an appropriate modification of the binaphthyl unit.

  DOI：

  10.1016/s0385-5414(07)00063-9

文献信息

• Oxidative desymmetrization of meso-cyclic ethers (2): Recognition of the core structure of substrates of the Mn(salen) catalyst
  作者：H SUEMATSU、Y TAMURA、H SHITAMA、T KATSUKI

  DOI：10.1016/s0385-5414(07)00063-9

  日期：2007.12.1

  Mn(salen) complexes bearing a binaphthyl chiral unit serve as catalysts for oxidative desymmetrization of meso-cyclic ethers. This study revealed that chiral recognition by the complex is strongly influenced by the core structure of substrates and this recognition is adjusted by an appropriate modification of the binaphthyl unit.