methyl (3aS,4R,9aR,10R,13aS,13dR)-4,10,13a-trimethyl-6-(propan-2-yl)-5-trifluoroacetyl-3a,4,5,8,9,9a,10,11,12,13,13a,13d-dodecahydro-3H-cyclopenta[c]naphtho[1,2-f]quinoline-10-carboxylate | 1556882-53-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: methyl (3aS,4R,9aR,10R,13aS,13dR)-4,10,13a-trimethyl-6-(propan-2-yl)-5-trifluoroacetyl-3a,4,5,8,9,9a,10,11,12,13,13a,13d-dodecahydro-3H-cyclopenta[c]naphtho[1,2-f]quinoline-10-carboxylate
• CAS: 1556882-53-1
• 化学式: C₃₀H₃₈F₃NO₃
• 分子量: 517.632
• InChiKey: TUTHMZRCGUCGOR-GCECVDFUSA-N

物化性质

• 熔点：
  158-162 °C(Solvent: Hexane)
• 沸点：
  560.5±50.0 °C(predicted)
• 密度：
  1.170±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为产物：
  描述：

  methyl (3aS,9aR,10R,13aS,13dR)-4,10,13a-trimethyl-6-(propan-2-yl)-3a,4,5,8,9,9a,10,11,12,13,13a,13d-dodecahydro-3H-cyclopenta[c]naphtho[1,2-f]quinoline-10-carboxylate 、 三氟乙酸酐 在 4-二甲氨基吡啶 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 生成 methyl (3aS,4R,9aR,10R,13aS,13dR)-4,10,13a-trimethyl-6-(propan-2-yl)-5-trifluoroacetyl-3a,4,5,8,9,9a,10,11,12,13,13a,13d-dodecahydro-3H-cyclopenta[c]naphtho[1,2-f]quinoline-10-carboxylate 、 methyl (3aS,4S,9aR,10R,13aS,13dR)-4,10,13a-trimethyl-6-(propan-2-yl)-5-trifluoroacetyl-3a,4,5,8,9,9a,10,11,12,13,13a,13d-dodecahydro-3H-cyclopenta[c]naphtho[1,2-f]quinoline-10-carboxylate
  参考文献：
  名称：

  Cyclocondensation of methyl 12-aminodehydroabietate with aldehydes and cyclopentadiene. Synthesis of tricyclic diterpenoide fused to tetrahydroquinoline

  摘要：

  Three-component cyclocondensation of methyl 12-aminodehydroabietate with cyclopentadiene and formaldehyde or acetaldehyde under acid catalysis afforded polysubstituted naphthoquinoline derivatives with fused oxetanocyclopentane and cyclopentene fragments. Ozonation of the double bond in the N-trifluoroacetyl cyclopentene derivatives gave the corresponding ozonide.

  DOI：

  10.1134/s1070428014010230