trans-AsPh4[IrCl4(CO)(pyridine)] | 1268481-47-5

• 英文名称: trans-AsPh4[IrCl4(CO)(pyridine)]
• 英文别名: trans-AsPh4[IrCl4(CO)(py)]
• CAS: 1268481-47-5
• 化学式: C₆H₅Cl₄IrNO*C₂₄H₂₀As
• 分子量: 824.488
• InChiKey: LPURWUIMISWPDX-UHFFFAOYSA-J

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  吡啶 、 、 氯化四苯砷 以 二氯甲烷 、 水 为溶剂， 以75%的产率得到trans-AsPh4[IrCl4(CO)(pyridine)]
  参考文献：
  名称：

  Tetrachlorocarbonyliridates: Water-Soluble Carbon Monoxide Releasing Molecules Rate-Modulated by the Sixth Ligand

  摘要：

  A new family of compounds is presented as potential carbon monoxide releasing molecules (CORMs). These compounds, based on tetrachlorocarbonyliridate(III) derivatives, were synthesized and fully characterized by X-ray diffraction, electrospray mass spectrometry, IR. NMR, and density functional theory calculations. The rate of CO release was studied via the myoglobin assay. The results showed that the rate depends on the nature of the sixth ligand, trans to CO, and that a significant modulation on the release rate can be produced by changing the ligand. The reported compounds are soluble in aqueous media, and the rates of CO release are comparable with those for known CORMs, releasing CO at a rate of 0.03-0.58 mu M min(-1) in a 10 mu M solution of myoglobin and 10 mu M of the complexes.

  DOI：

  10.1021/ic102038v