(12Z,17Z,20Z,23Z,26Z)-dotriaconta-12,17,20,23,26-pentaenoic acid | 1260225-97-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (12Z,17Z,20Z,23Z,26Z)-dotriaconta-12,17,20,23,26-pentaenoic acid
• CAS: 1260225-97-5
• 化学式: C₃₂H₅₄O₂
• 分子量: 470.78
• InChiKey: BPVFAUMKIODEGN-GXNRNZCVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.1
• 重原子数：
  34
• 可旋转键数：
  25
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.66
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (12Z,17Z,20Z,23Z,26Z)-dotriaconta-12,17,20,23,26-pentaen-1-ol 在 Jones reagent 作用下， 以 丙酮 为溶剂， 以83%的产率得到(12Z,17Z,20Z,23Z,26Z)-dotriaconta-12,17,20,23,26-pentaenoic acid
  参考文献：
  名称：

  Chemical synthesis of deuterium-labeled and unlabeled very long chain polyunsaturated fatty acids

  摘要：

  First syntheses of a deuterium-labeled very long C34-containing polyunsaturated fatty acid, 34:5n5, and three other unlabeled very long chain C30-32 containing polyunsaturated fatty acids are reported. These syntheses were achieved by coupling chemically modified C22- and C20-containing polyunsaturated fatty acids with carbanions derived from arylalkyl sulfones, followed by sodium amalgam-mediated desulfonylation. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.09.139

文献信息

• Chemical synthesis of deuterium-labeled and unlabeled very long chain polyunsaturated fatty acids
  作者：Ghulam M. Maharvi、Albert O. Edwards、Abdul H. Fauq

  DOI：10.1016/j.tetlet.2010.09.139

  日期：2010.12

  First syntheses of a deuterium-labeled very long C34-containing polyunsaturated fatty acid, 34:5n5, and three other unlabeled very long chain C30-32 containing polyunsaturated fatty acids are reported. These syntheses were achieved by coupling chemically modified C22- and C20-containing polyunsaturated fatty acids with carbanions derived from arylalkyl sulfones, followed by sodium amalgam-mediated desulfonylation. (C) 2010 Elsevier Ltd. All rights reserved.