| 1361028-54-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• CAS: 1361028-54-7
• 化学式: C₂₁H₂₂O₆
• 分子量: 370.402
• InChiKey: QUJPBHGPAXRCSG-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 aluminum (III) chloride 作用下， 以85.714%的产率得到
  参考文献：
  名称：

  Electronic tuning cyclization of aryl-1,4-enediones: AlCl3-mediated Nazarov-type cyclization to synthesize polysubstituted-1-indanones

  摘要：

  An electronic tuning Nazarov-type cyclization protocol was proposed for the synthesis of polysubstituted-1-indanones from the readily available starting materials 1,4-enediones. AlCl3 was highlighted as the most efficient promoter for this reaction. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.10.052

文献信息

• Efficient synthesis of isochromanones and isoquinolines via Yb(OTf)3-catalyzed tandem oxirane/aziridine ring opening/Friedel–Crafts cyclization
  作者：Lai Wei、Junliang Zhang

  DOI：10.1039/c2cc17836b

  日期：——

  The first example of Yb(OTf)(3)-catalyzed tandem ring opening/Friedel-Crafts cyclization of oxiranyl and aziridinyl ketones via selective C-C bond cleavage under mild conditions was developed. Isochromanones and isoquinolines are formed in reasonable yields, which often serve as building blocks for complex chemical synthesis.

  开发了Yb（OTf）（3）催化串联环开环/氧自由基和氮丙啶基酮在温和条件下通过选择性CC键裂解的弗里德-克来福特环化的第一个例子。异色酮和异喹啉以合理的产率形成，通常作为复杂化学合成的基础。