1-methoxy-2-[3-(nona-1,8-diyne-3-sulfonyl)prop-1-ynyl]benzene | 1214266-58-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-methoxy-2-[3-(nona-1,8-diyne-3-sulfonyl)prop-1-ynyl]benzene
• 英文别名: 1-Methoxy-2-(3-nona-1,8-diyn-3-ylsulfonylprop-1-ynyl)benzene；1-methoxy-2-(3-nona-1,8-diyn-3-ylsulfonylprop-1-ynyl)benzene
• CAS: 1214266-58-6
• 化学式: C₁₉H₂₀O₃S
• 分子量: 328.432
• InChiKey: YHNYKPCICWBDEE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  23
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  51.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-methoxy-2-[3-(nona-1,8-diyne-3-sulfonyl)prop-1-ynyl]benzene 在 三乙胺 作用下， 以 氯仿 为溶剂， 反应 72.0h， 以100%的产率得到1-hex-5-ynyl-5-methoxy-1,3-dihydro-naphtho[2,3-c]thiophene 2,2-dioxide
  参考文献：
  名称：

  Exploration of Braverman Reaction Chemistry. Synthesis of Tricyclic Dihydrothiophene Dioxide Derivatives from Bispropargyl Sulfones

  摘要：

  The base-mediated bicyclization Of unsymmetrical bispropargyl sulfones furnishes varying yields of dihydroisobenzothiophene dioxides through a presumed diradical intermediate. Attempts to trap a putative thiophene dioxide intermediate via Diels-Alder reaction with a pendant alkyne were not successful.

  DOI：

  10.3987/com-09-11840
• 作为产物：
  描述：

  C₁₉H₂₀OS 在 sodium carbonate 、 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以0.343 g的产率得到1-methoxy-2-[3-(nona-1,8-diyne-3-sulfonyl)prop-1-ynyl]benzene
  参考文献：
  名称：

  Exploration of Braverman Reaction Chemistry. Synthesis of Tricyclic Dihydrothiophene Dioxide Derivatives from Bispropargyl Sulfones

  摘要：

  The base-mediated bicyclization Of unsymmetrical bispropargyl sulfones furnishes varying yields of dihydroisobenzothiophene dioxides through a presumed diradical intermediate. Attempts to trap a putative thiophene dioxide intermediate via Diels-Alder reaction with a pendant alkyne were not successful.

  DOI：

  10.3987/com-09-11840

文献信息

• Exploration of Braverman Reaction Chemistry. Synthesis of Tricyclic Dihydrothiophene Dioxide Derivatives from Bispropargyl Sulfones
  作者：Ken S. Feldman、Brandon R. Selfridge

  DOI：10.3987/com-09-11840

  日期：——

  The base-mediated bicyclization Of unsymmetrical bispropargyl sulfones furnishes varying yields of dihydroisobenzothiophene dioxides through a presumed diradical intermediate. Attempts to trap a putative thiophene dioxide intermediate via Diels-Alder reaction with a pendant alkyne were not successful.