(E)-tributyl(1-(2,6-dichlorophenyl)-2-(4-methoxyphenyl)-vinyl)stannane | 1258379-76-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (E)-tributyl(1-(2,6-dichlorophenyl)-2-(4-methoxyphenyl)-vinyl)stannane
• CAS: 1258379-76-8
• 化学式: C₂₇H₃₈Cl₂OSn
• 分子量: 568.214
• InChiKey: ZRUSPDAVDGGJMB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.93
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (E)-tributyl(1-(2,6-dichlorophenyl)-2-(4-methoxyphenyl)-vinyl)stannane 在 碘 作用下， 以 二氯甲烷 为溶剂， 生成 (E)-1,3-dichloro-2-(1-iodo-2-(4-methoxyphenyl)vinyl) benzene
  参考文献：
  名称：

  Regioselective hydrostannation of highly hindered arylalkynes under ortho-directing effects

  摘要：

  Palladium-catalyzed hydrostannation reactions of ortho-disubstituted arylalkynes were achieved with total stereo- and regio-selectivity in THF at room temperature. The regioselectivity was found to be under the control of the ortho-substituents (ortho-directing effects. ODE) and pure alpha-vinylstannanes are produced in good yields and as single isomers regardless of the substituents' nature. These hydrostannation alpha-products are precursors of choice for the preparation of stereo-defined triarylolefins. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2010.09.010

文献信息

• Regioselective hydrostannation of highly hindered arylalkynes under ortho-directing effects
  作者：Abdallah Hamze、Patrick Le Menez、Olivier Provot、Estelle Morvan、Jean-Daniel Brion、Mouâd Alami

  DOI：10.1016/j.tet.2010.09.010

  日期：2010.11

  Palladium-catalyzed hydrostannation reactions of ortho-disubstituted arylalkynes were achieved with total stereo- and regio-selectivity in THF at room temperature. The regioselectivity was found to be under the control of the ortho-substituents (ortho-directing effects. ODE) and pure alpha-vinylstannanes are produced in good yields and as single isomers regardless of the substituents' nature. These hydrostannation alpha-products are precursors of choice for the preparation of stereo-defined triarylolefins. (C) 2010 Elsevier Ltd. All rights reserved.