N-[1-cyano-2-(3,6-dichloro-2H-pyrazolo[4,3-b]pyridin-2-yl)-1-methylethyl]-4-trifluoromethoxybenzamide | 1086836-51-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡唑并吡啶类
• 英文名称: N-[1-cyano-2-(3,6-dichloro-2H-pyrazolo[4,3-b]pyridin-2-yl)-1-methylethyl]-4-trifluoromethoxybenzamide
• 英文别名: N-[2-cyano-1-(3,6-dichloropyrazolo[4,3-b]pyridin-2-yl)propan-2-yl]-4-(trifluoromethoxy)benzamide
• CAS: 1086836-51-2
• 化学式: C₁₈H₁₂Cl₂F₃N₅O₂
• 分子量: 458.227
• InChiKey: IIRORHYEUDWTCR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  92.8
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  N-[2-(6-chloro-2H-pyrazolo[4,3-b]pyridin-2-yl)-1-cyano-1-methylethyl]-4-trifluoromethoxybenzamide 在 N-氯代丁二酰亚胺 作用下， 以 乙腈 为溶剂， 以89%的产率得到N-[1-cyano-2-(3,6-dichloro-2H-pyrazolo[4,3-b]pyridin-2-yl)-1-methylethyl]-4-trifluoromethoxybenzamide
  参考文献：
  名称：

  ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF

  摘要：

  本发明涉及新颖的式(I)的芳基咪唑-2-基-氰基乙基氨基衍生物：其中R3、R4、R5、R6、R7、P、Q、V、W、X、Y、Z和a如描述中所定义，以及其组合物、制备方法以及它们作为杀虫剂的用途。

  公开号：

  US20140080862A1

文献信息

• ENANTIOMERICALLY ENRICHED ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF
  申请人：Soll Mark David

  公开号：US20100125089A1

  公开（公告）日：2010-05-20

  The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives substantially enriched in an enantiomer of formula (I): and compounds of formula (IH) wherein R 3 , R 4 , R 5 , R 6 , R 7 , R 13a , R 13b , R 14a , R 14b , P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.

  本发明涉及一种在式(I)的对映体方面显著富集的新颖芳基唑-2-基-氰基乙基氨基衍生物： 以及式(IH)的化合物 其中R3、R4、R5、R6、R7、R13a、R13b、R14a、R14b、P、Q、V、W、X、Y、Z和a如描述中所定义，以及它们的组合物、其制备方法以及它们作为杀虫剂的用途。
• Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
  申请人：Merial Limited

  公开号：US08283475B2

  公开（公告）日：2012-10-09

  The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I): wherein R3, R4, R5, R6, R7, P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.

  本发明涉及新型的式(I)的芳基氮杂二烯-2-基-氰基乙基氨基衍生物：其中R3、R4、R5、R6、R7、P、Q、V、W、X、Y、Z和a如描述中所定义，以及其组合物、制备方法和用作农药的用途。
• Enantiomerically enriched aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
  申请人：Soll Mark David

  公开号：US08461176B2

  公开（公告）日：2013-06-11

  The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives substantially enriched in an enantiomer of formula (I): and compounds of formula (IH) wherein R3, R4, R5, R6, R7, R13a, R13b, R14a, R14b, P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.

  本发明涉及一种新的芳基氮杂苯-2-基-氰基乙基氨基衍生物，其在式(I)的对映体方面得到了显著的富集，以及式(IH)的化合物，其中R3、R4、R5、R6、R7、R13a、R13b、R14a、R14b、P、Q、V、W、X、Y、Z和a如描述中所定义的，以及其组成物、制备方法和其作为杀虫剂的用途。
• ENANTIOMERIALLY ENRICHED ARYLOAZOL-2-YL CYANOETHYLAMINO PARACITICIDAL COMPOUNDS
  申请人：Merial, Inc.

  公开号：EP3050874A1

  公开（公告）日：2016-08-03

  The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives substantially enriched in an enantiomer of formula (I): and compounds of formula (IH) wherein R3, R4, R5, R6, R7, R13a, R13b, R14a, R14b, P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.

  本发明涉及新型芳基唑-2-基-氰乙基氨基衍生物，该衍生物大量富含式（I）的对映体： 和式(IH)化合物 其中 R3、R4、R5、R6、R7、R13a、R13b、R14a、R14b、P、Q、V、W、X、Y、Z 和 a 如描述中所定义，其组合物、制备工艺及其作为农药的用途。
• ENANTIOMERICALLY ENRICHED ARYLOAZOL-2-YL CYANOETHYLAMINO PARASITICIDAL COMPOUNDS
  申请人：Merial, Inc.

  公开号：EP3498696A1

  公开（公告）日：2019-06-19

  The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives substantially enriched in an enantiomer of formula (I): and compounds of formula (IH) wherein R3, R4, R5, R6, R7, R13a, R13b, R14a, R14b, P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.

  本发明涉及新型芳基唑-2-基-氰乙基氨基衍生物，该衍生物大量富含式（I）的对映体： 和式(IH)化合物 其中 R3、R4、R5、R6、R7、R13a、R13b、R14a、R14b、P、Q、V、W、X、Y、Z 和 a 如描述中所定义，本发明还涉及其组合物、制备工艺及其作为农药的用途。