diethyl 2-[[(3aR,4S,7R,7aR)-2,2-dimethyl-7-phenylmethoxy-4-[[(1S,2R,6R,8R,9S)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl]methoxy]-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyridin-5-yl]methylidene]propanedioate | 1011245-17-2

分子结构分类

有机化合物 - 有机杂环化合物 - 二氧吡喃

中文名称

——

中文别名

——

英文名称

diethyl 2-[[(3aR,4S,7R,7aR)-2,2-dimethyl-7-phenylmethoxy-4-[[(1S,2R,6R,8R,9S)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl]methoxy]-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyridin-5-yl]methylidene]propanedioate

英文别名

——

diethyl 2-[[(3aR,4S,7R,7aR)-2,2-dimethyl-7-phenylmethoxy-4-[[(1S,2R,6R,8R,9S)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl]methoxy]-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyridin-5-yl]methylidene]propanedioate化学式

CAS

1011245-17-2

化学式

C₃₅H₄₉NO₁₃

mdl

——

分子量

691.773

InChiKey

CWJOUKLWURLTDC-SEHAEYRKSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

3.2
重原子数：

49
可旋转键数：

13
环数：

6.0
sp3杂化的碳原子比例：

0.71
拓扑面积：

139
氢给体数：

0
氢受体数：

14

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	diethyl 2-[[(3aR,4S,7R,7aR)-4-ethylsulfanyl-2,2-dimethyl-7-phenylmethoxy-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyridin-5-yl]methylidene]propanedioate	1011245-14-9	C₂₅H₃₅NO₇S	493.621

反应信息

作为产物：

描述：

diethyl 2-[[(3aR,4S,7R,7aR)-4-ethylsulfanyl-2,2-dimethyl-7-phenylmethoxy-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyridin-5-yl]methylidene]propanedioate 、双丙酮半乳糖在 DMTST 作用下，以乙腈为溶剂，反应 2.0h，以80%的产率得到diethyl 2-[[(3aR,4S,7R,7aR)-2,2-dimethyl-7-phenylmethoxy-4-[[(1S,2R,6R,8R,9S)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl]methoxy]-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyridin-5-yl]methylidene]propanedioate

参考文献：

名称：

Iminosugar thioglycosides as glycosyl donors: a route to disaccharides with an iminosugar moiety

摘要：

The immosugar thioglycosides are used as glycosyl donors in glycosidation reactions. Thereby, iminosugar glycosides and disaccharide analogues with an iminosugar moiety are prepared. The yields are high and the method is stereoselective. (C) 2007 Elsevier Ltd. All rights reserved.

DOI：

10.1016/j.tetlet.2007.11.160

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文献信息

Iminosugar thioglycosides as glycosyl donors: a route to disaccharides with an iminosugar moiety

作者：José Fuentes、Nader R. Al Bujuq、Manuel Angulo、Consolación Gasch

DOI：10.1016/j.tetlet.2007.11.160

日期：2008.1

The immosugar thioglycosides are used as glycosyl donors in glycosidation reactions. Thereby, iminosugar glycosides and disaccharide analogues with an iminosugar moiety are prepared. The yields are high and the method is stereoselective. (C) 2007 Elsevier Ltd. All rights reserved.

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