Dimethyl 2-(benzenesulfonyl)-6,7,15,17-tetrahydrocyclopenta[a]phenanthrene-16,16-dicarboxylate | 1001160-19-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: Dimethyl 2-(benzenesulfonyl)-6,7,15,17-tetrahydrocyclopenta[a]phenanthrene-16,16-dicarboxylate
• 英文别名: dimethyl 2-(benzenesulfonyl)-6,7,15,17-tetrahydrocyclopenta[a]phenanthrene-16,16-dicarboxylate
• CAS: 1001160-19-5
• 化学式: C₂₇H₂₄O₆S
• 分子量: 476.55
• InChiKey: XKUMXCWHTXLJBM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  34
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  95.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  在 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 甲苯 为溶剂， 反应 7.0h， 以26 mg的产率得到Dimethyl 2-(benzenesulfonyl)-6,7,15,17-tetrahydrocyclopenta[a]phenanthrene-16,16-dicarboxylate
  参考文献：
  名称：

  Rh-Catalyzed Triple Allene Approach to Bicyclo[4.4.0]decene Derivatives and Its Application for the Stepwise Synthesis of Steroid-Like Tetracyclic Skeletons

  摘要：

  The construction of a new type of bicyclo[4.4.0]decene products with a conjugated exocyclic diene unit was developed using Rh-catalyzed cyclization of 1,5-bisallenes in the presence of monoallenes. The steroid-like tetracyclic products could be obtained by applying an alkylation-Diels-Alder process.

  DOI：

  10.1021/ol702557s

文献信息

• Rh-Catalyzed Triple Allene Approach to Bicyclo[4.4.0]decene Derivatives and Its Application for the Stepwise Synthesis of Steroid-Like Tetracyclic Skeletons
  作者：Ping Lu、Shengming Ma

  DOI：10.1021/ol702557s

  日期：2007.12.1

  The construction of a new type of bicyclo[4.4.0]decene products with a conjugated exocyclic diene unit was developed using Rh-catalyzed cyclization of 1,5-bisallenes in the presence of monoallenes. The steroid-like tetracyclic products could be obtained by applying an alkylation-Diels-Alder process.