6-Fluor-5-hydroxy-2-methyl-indol-3-carbonsaeure-ethylester | 16052-44-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 6-Fluor-5-hydroxy-2-methyl-indol-3-carbonsaeure-ethylester
• 英文别名: 6-fluoro-5-hydroxy-2-methyl-indole-3-carboxylic acid ethyl ester；ethyl 6-fluoro-5-hydroxy-2-methyl-1H-indole-3-carboxylate
• CAS: 16052-44-1
• 化学式: C₁₂H₁₂FNO₃
• 分子量: 237.231
• InChiKey: BCUXYDUSHMVTPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  62.3
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS
  申请人：WARNER-LAMBERT COMPANY

  公开号：EP1144415A2

  公开（公告）日：2001-10-17
• [EN] FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS<br/>[FR] HETEROCYCLES FONCTIONNALISES EN TANT QUE MODULATEURS DES RECEPTEURS DE CHIMIOKINES
  申请人：WARNER LAMBERT CO

  公开号：WO2000042045A2

  公开（公告）日：2000-07-20

  The present invention is a novel series of functionalized heterocycles as chemokine receptor modulators of Formula (I) useful as modulators of chemokine receptor activity. The compounds are useful in the treatment and prevention of the AIDS virus. Intermediates useful in the prepartion of the final products, pharmaceutical compositions containing the final products are also taught.